Anti-Inflammatory Potentials of the n-Hexane Fraction of
Alstonia boonei
endotoxins
inflammatory cytokines
liquid chromatography-mass spectrometry
Journal
Journal of inflammation research
ISSN: 1178-7031
Titre abrégé: J Inflamm Res
Pays: New Zealand
ID NLM: 101512684
Informations de publication
Date de publication:
2021
2021
Historique:
received:
23
03
2021
accepted:
25
05
2021
entrez:
25
8
2021
pubmed:
26
8
2021
medline:
26
8
2021
Statut:
epublish
Résumé
Inflammation is a protective response of the host to infections and tissue damage and medicinal plants have been used to regulate inflammatory response. The phytochemical contents of the A quantity of 5 mg/kg lipopolysaccharide (LPS) was used to induce inflammation in twenty-five male Wistar rats, grouped (n = 5) and treated as follows: negative control (10 mL/kg saline), positive control (1 mg/kg ibuprofen); 50, 100 and 20 mg/kg of the Calcium induced mPT in 8 fold and LPS induced mPT 14 fold in the negative control while the These results showed that bioactive phytochemicals present in the
Sections du résumé
BACKGROUND
BACKGROUND
Inflammation is a protective response of the host to infections and tissue damage and medicinal plants have been used to regulate inflammatory response. The phytochemical contents of the
MATERIALS AND METHODS
METHODS
A quantity of 5 mg/kg lipopolysaccharide (LPS) was used to induce inflammation in twenty-five male Wistar rats, grouped (n = 5) and treated as follows: negative control (10 mL/kg saline), positive control (1 mg/kg ibuprofen); 50, 100 and 20 mg/kg of the
RESULTS
RESULTS
Calcium induced mPT in 8 fold and LPS induced mPT 14 fold in the negative control while the
CONCLUSION
CONCLUSIONS
These results showed that bioactive phytochemicals present in the
Identifiants
pubmed: 34429627
doi: 10.2147/JIR.S304076
pii: 304076
pmc: PMC8376584
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3905-3920Informations de copyright
© 2021 Olanlokun et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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