Correlation between the prevalence of T-cell lymphomas and alcohol consumption.
T-cell lymphomas
alcohol consumption
pathophysiology
Journal
Medicine and pharmacy reports
ISSN: 2668-0572
Titre abrégé: Med Pharm Rep
Pays: Romania
ID NLM: 101742144
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
13
06
2020
revised:
27
11
2020
accepted:
29
03
2021
entrez:
25
8
2021
pubmed:
26
8
2021
medline:
26
8
2021
Statut:
ppublish
Résumé
Alcohol is a psychoactive substance that causes dependence, with many thousands of years in the history of mankind, being widely used in different cultures. According to the International Agency for Research on Cancer, alcohol is involved in the development of cancer, being directly associated with it. Considering that alcohol is involved in the initiation and dissemination of gastrointestinal malignancies, the objective of the study was to assess its role in the pathogenesis of T-cell lymphomas, as well as its possible correlation with chronic consumption. The patient cohort was compiled from the Sixth Medical Center of the People's Liberation Army Navy General Hospital in Beijing, China. A total of 30 patients matched the criteria and were enrolled in the study. Statistical analysis of the raw data was performed using R Statistics version R 3.5.1. released on the 29.08.2018. Our data demonstrate that the most common extranodal involvment of T-cell lymphoma patients is represented in decreasing order by bone marrow, peritoneum, rhino-oropharynx and the liver-biliary system. Nodal involvement is mainly represented in decreasing order by the laterocervical, axillary, mediastinal and inguinal regions. These findings may be of value in further research and practical/clinical settings. Fever is the most common clinical feature and was present in most studied patients.
Sections du résumé
BACKGROUND AND AIMS
OBJECTIVE
Alcohol is a psychoactive substance that causes dependence, with many thousands of years in the history of mankind, being widely used in different cultures. According to the International Agency for Research on Cancer, alcohol is involved in the development of cancer, being directly associated with it. Considering that alcohol is involved in the initiation and dissemination of gastrointestinal malignancies, the objective of the study was to assess its role in the pathogenesis of T-cell lymphomas, as well as its possible correlation with chronic consumption.
METHODS
METHODS
The patient cohort was compiled from the Sixth Medical Center of the People's Liberation Army Navy General Hospital in Beijing, China. A total of 30 patients matched the criteria and were enrolled in the study. Statistical analysis of the raw data was performed using R Statistics version R 3.5.1. released on the 29.08.2018.
RESULTS
RESULTS
Our data demonstrate that the most common extranodal involvment of T-cell lymphoma patients is represented in decreasing order by bone marrow, peritoneum, rhino-oropharynx and the liver-biliary system. Nodal involvement is mainly represented in decreasing order by the laterocervical, axillary, mediastinal and inguinal regions.
CONCLUSIONS
CONCLUSIONS
These findings may be of value in further research and practical/clinical settings. Fever is the most common clinical feature and was present in most studied patients.
Identifiants
pubmed: 34430851
doi: 10.15386/mpr-1777
pii: cm-94-298
pmc: PMC8357363
doi:
Types de publication
Journal Article
Langues
eng
Pagination
298-306Références
Am J Surg Pathol. 2020 Aug;44(8):1061-1072
pubmed: 32317607
Addiction. 2004 Feb;99(2):161-4
pubmed: 14756708
J Subst Abuse Treat. 2009 Jan;36(1):75-86
pubmed: 18657940
Addiction. 2014 Jun;109(6):880-93
pubmed: 24467748
JCO Glob Oncol. 2020 Apr;6:548-556
pubmed: 32243210
Hum Pathol. 2016 Jul;53:192-4
pubmed: 27016488
Alcohol Clin Exp Res. 2007 Dec;31(12):2092-100
pubmed: 17949463
Dtsch Med Wochenschr. 2006 Mar 31;131(13):685-90
pubmed: 16555177
Front Biosci. 2005 Jan 01;10:951-60
pubmed: 15569633
Addiction. 2017 Nov;112(11):1920-1930
pubmed: 28556302
Lancet Psychiatry. 2018 Dec;5(12):987-1012
pubmed: 30392731
Crit Rev Clin Lab Sci. 2018 Mar;55(2):102-114
pubmed: 29316828
Addiction. 2010 Jul;105(7):1192-202
pubmed: 20456295
Curr Hematol Malig Rep. 2016 Dec;11(6):514-527
pubmed: 27778143
Annu Rev Clin Psychol. 2016;12:29-51
pubmed: 26565120
J Clin Med. 2020 Oct 24;9(11):
pubmed: 33114418
Eur J Haematol. 2008 Jan;80(1):55-60
pubmed: 18028433
Hepatol Commun. 2017 Jul 13;1(7):675-690
pubmed: 29404485
Cancer Causes Control. 2020 Jun;31(6):583-599
pubmed: 32314107
Cell Physiol Biochem. 2020 Oct 3;54(5):994-1012
pubmed: 33006449
Curr Hematol Malig Rep. 2016 Dec;11(6):492-503
pubmed: 27995419
Int J Mol Sci. 2017 May 24;18(6):
pubmed: 28538665
Alcohol Res Health. 2007;30(1):38-41, 44-7
pubmed: 17718399
Lancet Haematol. 2020 Apr;7(4):e284-e294
pubmed: 32105608
Ecancermedicalscience. 2020 Apr 20;14:1025
pubmed: 32346391
Addiction. 2018 Oct;113(10):1905-1926
pubmed: 29749059
J Epidemiol Community Health. 2008 Aug;62(8):728-33
pubmed: 18621959
Lancet Oncol. 2006 Feb;7(2):149-56
pubmed: 16455479
Alcohol Res Health. 2006;29(4):245-54
pubmed: 17718403
Lancet. 2020 Mar 28;395(10229):1020-1021
pubmed: 32222185
Addiction. 2004 Apr;99(4):419-24
pubmed: 15049741
Drug Alcohol Rev. 2020 Sep;39(6):624-631
pubmed: 32250491
Hematol Oncol. 2019 Dec;37(5):578-585
pubmed: 31702065
J Cancer Surviv. 2010 Jun;4(2):101-9
pubmed: 20039144
Health Expect. 2020 Aug;23(4):802-812
pubmed: 32329938
Alcohol Res. 2016;38(1):83-94
pubmed: 27159815
Lancet. 2012 Sep 1;380(9844):848-57
pubmed: 22835603
CA Cancer J Clin. 2020 Jan;70(1):47-70
pubmed: 31815293
Maturitas. 2014 Jan;77(1):7-11
pubmed: 24215727
Ann Oncol. 2006 Aug;17(8):1283-9
pubmed: 16728483
J Subst Abuse. 2000;12(1-2):1-21
pubmed: 11288465
J Am Acad Dermatol. 2014 Jun;70(6):1002-9
pubmed: 24629518
Leukemia. 2020 Aug;34(8):2243-2248
pubmed: 32066865
Clin Chim Acta. 2008 Sep;395(1-2):1-5
pubmed: 18505683
Cancer. 2010 Jun 15;116(12):2993-3000
pubmed: 20564404