Amiodarone-Induced Thyroid Storm Causing Sustained Monomorphic Ventricular Tachycardia Treated With Plasmapheresis: A Challenging Clinical Case.
Amiodarone
Plasmapheresis
Thyroid storm
Thyrotoxicosis
Ventricular tachycardia
Journal
Journal of medical cases
ISSN: 1923-4155
Titre abrégé: J Med Cases
Pays: Canada
ID NLM: 101551824
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
04
03
2020
accepted:
16
03
2020
entrez:
26
8
2021
pubmed:
1
3
2020
medline:
1
3
2020
Statut:
ppublish
Résumé
Thyroid storm is a rare endocrine emergency with a high mortality rate approaching 20%. It manifests with the exaggerated symptoms of hyperthyroidism including hyperpyrexia, hypotension, cardiac arrhythmias, and death. The mainstay of treatment includes supportive intensive care and initiation of thionamides, beta blockers, corticosteroids, and if necessary anti-arrhythmics in the presence of refractory ventricular arrhythmias. We describe a case of amiodarone-induced thyrotoxicosis and thyroid storm leading to refractory ventricular tachycardias treated with plasmapheresis when anti-arrhythmic therapy became contraindicated. Amiodarone-induced thyroid storm can lead to monomorphic ventricular tachycardia. Under the circumstances of limited medical therapies, plasmapheresis can be an effective treatment option.
Identifiants
pubmed: 34434369
doi: 10.14740/jmc3450
pmc: PMC8383526
doi:
Types de publication
Case Reports
Langues
eng
Pagination
79-81Informations de copyright
Copyright 2020, Upadhyaya et al.
Déclaration de conflit d'intérêts
None to declare.
Références
J Clin Endocrinol Metab. 1996 Aug;81(8):2930-3
pubmed: 8768854
South Med J. 2004 Jun;97(6):604-7
pubmed: 15255432
Ther Apher Dial. 2011 Dec;15(6):522-31
pubmed: 22107688
Endocrinol Metab Clin North Am. 2006 Dec;35(4):663-86, vii
pubmed: 17127140
Endocrine. 2018 Oct;62(1):144-148
pubmed: 29968224
J Clin Endocrinol Metab. 2009 Jan;94(1):109-14
pubmed: 18940876
Endocr Rev. 2001 Apr;22(2):240-54
pubmed: 11294826
Endocrinol Metab Clin North Am. 1993 Jun;22(2):263-77
pubmed: 8325286
J Clin Endocrinol Metab. 2015 Feb;100(2):451-9
pubmed: 25343237
Thyroid. 2019 Jan;29(1):36-43
pubmed: 30382003