A Systematic Review to Clarify the Prognostic Values of CD44 and CD44

CD44 CD44/CD24 cancer stem cell cancer therapeutic resistance prognosis triple-negative breast cancer

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2021
Historique:
received: 01 04 2021
accepted: 21 07 2021
entrez: 26 8 2021
pubmed: 27 8 2021
medline: 27 8 2021
Statut: epublish

Résumé

As a unique population of tumor bulk, cancer stem cells have been implicated in tumor relapse and chemoresistance in triple-negative breast cancer (TNBC). Therefore, understanding the phenotype of cancer stem cells can pave the way for introducing novel molecular targeted therapies for treating TNBC patients. Preclinical studies have identified CD44

Identifiants

pubmed: 34434894
doi: 10.3389/fonc.2021.689839
pmc: PMC8381605
doi:

Types de publication

Systematic Review

Langues

eng

Pagination

689839

Informations de copyright

Copyright © 2021 Abdoli Shadbad, Hosseinkhani, Asadzadeh, Derakhshani, Karim Ahangar, Hemmat, Lotfinejad, Brunetti, Silvestris and Baradaran.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Mahdi Abdoli Shadbad (M)

Research Center for Evidence-Based Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Negar Hosseinkhani (N)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Zahra Asadzadeh (Z)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Afshin Derakhshani (A)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.

Noora Karim Ahangar (N)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Nima Hemmat (N)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Parisa Lotfinejad (P)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Oronzo Brunetti (O)

Medical Oncology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Tumori Giovanni Paolo II, Bari, Italy.

Nicola Silvestris (N)

Medical Oncology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Tumori Giovanni Paolo II, Bari, Italy.
Department of Biomedical Sciences and Human Oncology, Aldo Moro University of Bari, Bari, Italy.

Behzad Baradaran (B)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Classifications MeSH