Simultaneous Temperature Measurements and Aerosol Collection During Vaping for the Analysis of Δ
EVALI
ceramic coil
temperature
vaping
vitamin E acetate
Δ9 -tetrahydrocannabinol
Journal
Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988
Informations de publication
Date de publication:
2021
2021
Historique:
received:
01
07
2021
accepted:
27
07
2021
entrez:
26
8
2021
pubmed:
27
8
2021
medline:
27
8
2021
Statut:
epublish
Résumé
Incidence of e-cigarette, or vaping, product use-associated lung injury (EVALI) has been linked to the vaping of tetrahydrocannabinol (THC) products to which vitamin E acetate (VEA) has been added. In this work we vaped THC/VEA mixtures at elevated power levels using a variety of ceramic coil vaping cartridges and a commercially available vaping device, while simultaneously measuring temperature and collecting the vaporized condensate. The collected vapor condensate was analyzed for evidence of VEA decomposition by GC/MS, GC/FT-IR/MS, and LC-APCI-HRMS/MS. Mean temperature maxima for all examined cartridges at the selected power exceeded 430°C, with a range of 375-569°C, well beyond that required for thermal decomposition of VEA. The percent recovery of VEA and Δ
Identifiants
pubmed: 34434923
doi: 10.3389/fchem.2021.734793
pii: 734793
pmc: PMC8381023
doi:
Types de publication
Journal Article
Langues
eng
Pagination
734793Informations de copyright
Copyright © 2021 Lynch, Lorenz, Brueggemeyer, Lanzarotta, Falconer and Wilson.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Environ Res. 2016 Aug;149:151-156
pubmed: 27200479
Toxics. 2020 Apr 03;8(2):
pubmed: 32260052
Forensic Sci Int. 2018 Aug;289:429-437
pubmed: 29954632
ACS Omega. 2019 Sep 16;4(14):16111-16120
pubmed: 31592479
Int J Hyg Environ Health. 2016 May;219(3):268-77
pubmed: 26847410
Chem Res Toxicol. 2020 Aug 17;33(8):2157-2163
pubmed: 32618192
Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6349-6355
pubmed: 32156732
N Engl J Med. 2020 Feb 20;382(8):697-705
pubmed: 31860793
Int J Environ Res Public Health. 2018 Aug 28;15(9):
pubmed: 30154301
Biochem Pharmacol. 1978 Feb 15;27(4):607-8
pubmed: 629821
Aerosol Sci Technol. 2020;54(9):993-998
pubmed: 33132476
Aerosol Sci Technol. 2017;51(1):1-11
pubmed: 28706340
J Toxicol Sci. 2015 Dec;40(6):797-803
pubmed: 26558460
N Engl J Med. 2020 Mar 19;382(12):1175-1177
pubmed: 32101656
Rev Environ Contam Toxicol. 1987;99:61-81
pubmed: 3039589
Anal Chem. 2020 Feb 4;92(3):2374-2378
pubmed: 31951379
PLoS One. 2018 Nov 5;13(11):e0206937
pubmed: 30395592
Science. 1970 Jun 5;168(3936):1159-66
pubmed: 4910003
Sci Rep. 2016 May 26;6:25599
pubmed: 27228348
J Chromatogr. 1975 May 21;108(2):375-9
pubmed: 1127061
Forensic Sci Int. 2018 Aug;289:438-447
pubmed: 30025568
Chem Res Toxicol. 2018 Jan 16;31(1):4-12
pubmed: 29161504