REGN1908-1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics.


Journal

Clinical and translational science
ISSN: 1752-8062
Titre abrégé: Clin Transl Sci
Pays: United States
ID NLM: 101474067

Informations de publication

Date de publication:
11 2021
Historique:
pubmed: 27 8 2021
medline: 10 2 2022
entrez: 26 8 2021
Statut: ppublish

Résumé

REGN1908-1909, a 1:1 cocktail of two fully human IgG

Identifiants

pubmed: 34437752
doi: 10.1111/cts.13112
pmc: PMC8604232
doi:

Substances chimiques

Allergens 0
Anti-Allergic Agents 0
Antibodies, Monoclonal 0

Banques de données

ClinicalTrials.gov
['NCT01922661']

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2440-2449

Subventions

Organisme : Regeneron Pharmaceuticals

Informations de copyright

© 2021 Regeneron Pharmaceuticals, Inc. Clinical and Translational Science published by Wiley Periodicals LLC on behalf of the American Society for Clinical Pharmacology and Therapeutics.

Références

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pubmed: 19844127
Nat Commun. 2018 Apr 12;9(1):1421
pubmed: 29650949
J Allergy Clin Immunol. 2017 Dec;140(6):1485-1498
pubmed: 29221580
J Allergy Clin Immunol. 1999 Dec;104(6):1223-30
pubmed: 10589005
Allergy. 2012 Feb;67(2):217-26
pubmed: 22077562
Am J Respir Crit Care Med. 2021 Jul 1;204(1):23-33
pubmed: 33651675
J Allergy Clin Immunol. 2005 Sep;116(3):608-13
pubmed: 16159631
Curr Opin Allergy Clin Immunol. 2004 Aug;4(4):313-8
pubmed: 15238798
Clin Transl Sci. 2021 Nov;14(6):2440-2449
pubmed: 34437752
Nat Med. 2012 May 04;18(5):693-704
pubmed: 22561833
J Exp Med. 1935 Nov 30;62(6):733-50
pubmed: 19870445
J Allergy Clin Immunol. 2014 Aug;134(2):350-9
pubmed: 24522093
World Allergy Organ J. 2015 May 14;8(1):17
pubmed: 26023323
Allergy. 2019 Nov;74(11):2087-2102
pubmed: 30955224
Allergy. 2010 Dec;65(12):1525-30
pubmed: 21039596
J Allergy Clin Immunol. 2009 May;123(5):1189-91
pubmed: 19362358
Clin Pharmacokinet. 2011 Feb;50(2):131-42
pubmed: 21241072
Curr Opin Allergy Clin Immunol. 2018 Aug;18(4):350-355
pubmed: 29870462

Auteurs

Mohamed A Kamal (MA)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Robert Dingman (R)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Claire Q Wang (CQ)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Ching-Ha Lai (CH)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Manoj Rajadhyaksha (M)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Michelle DeVeaux (M)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Jamie M Orengo (JM)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

Allen Radin (A)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

John D Davis (JD)

Regeneron Pharmaceuticals, Tarrytown, NY, USA.

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Classifications MeSH