Kidney Dysfunction Is Associated with Thrombosis and Disease Severity in Myeloproliferative Neoplasms: Implications from the German Study Group for MPN Bioregistry.
JAK2V617F
bleeding
chronic kidney disease
essential thrombocythemia (ET)
myeloproliferative neoplasms (MPN)
polycythemia vera (PV)
primary myelofibrosis (PMF)
renal dysfunction
thromboembolism
thrombosis
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
13 Aug 2021
13 Aug 2021
Historique:
received:
15
06
2021
revised:
29
07
2021
accepted:
10
08
2021
entrez:
27
8
2021
pubmed:
28
8
2021
medline:
28
8
2021
Statut:
epublish
Résumé
Inflammation-induced thrombosis represents a severe complication in patients with myeloproliferative neoplasms (MPN) and in those with kidney dysfunction. Overlapping disease-specific attributes suggest common mechanisms involved in MPN pathogenesis, kidney dysfunction, and thrombosis. Data from 1420 patients with essential thrombocythemia (ET, 33.7%), polycythemia vera (PV, 38.5%), and myelofibrosis (MF, 27.9%) were extracted from the bioregistry of the German Study Group for MPN. The total cohort was subdivided according to the calculated estimated glomerular filtration rate (eGFR, (mL/min/1.73 m
Identifiants
pubmed: 34439237
pii: cancers13164086
doi: 10.3390/cancers13164086
pmc: PMC8393882
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Stiftung Universitätsmedizin of RWTH Aachen University
ID : KK, THB, and SK
Organisme : Deutsche Forschungsgemeinschaft
ID : BR 1782/5-1
Organisme : Deutsche Forschungsgemeinschaft
ID : KO 2155/7-1
Organisme : Interdisciplinary Center for Clinical Research, Faculty of Medicine, RWTH Aachen University
ID : IZKF O3-7
Références
Am J Hematol. 2012 Mar;87(3):319-20
pubmed: 22190201
Ann Intern Med. 2018 Mar 6;168(5):317-325
pubmed: 29335713
Clin Exp Nephrol. 2003 Dec;7(4):296-300
pubmed: 14712360
Blood. 2011 Jun 2;117(22):5857-9
pubmed: 21490340
Ann Intern Med. 2009 May 5;150(9):604-12
pubmed: 19414839
Blood. 2012 Aug 16;120(7):1409-11
pubmed: 22709688
Clin J Am Soc Nephrol. 2008 Sep;3(5):1526-33
pubmed: 18701615
Blood. 2007 Mar 15;109(6):2446-52
pubmed: 17105814
Haematologica. 2019 Nov;104(11):e506-e509
pubmed: 30948490
Kidney Int. 2017 Apr;91(4):797-807
pubmed: 28040264
JAMA. 2010 Feb 3;303(5):423-9
pubmed: 20124537
Leukemia. 2012 Apr;26(4):563-71
pubmed: 22076463
Ann Hematol. 2019 May;98(5):1071-1082
pubmed: 30848334
Cancer Med. 2020 Mar;9(6):2096-2105
pubmed: 31994332
Blood. 2014 Mar 6;123(10):1544-51
pubmed: 24366362
Ann Hematol. 2014 Dec;93(12):1953-63
pubmed: 25307456
Leukemia. 2008 Jan;22(1):14-22
pubmed: 17882280
Am J Kidney Dis. 2003 Jan;41(1):1-12
pubmed: 12500213
Kidney Int. 2007 Jan;71(2):159-66
pubmed: 17136030
Kidney Int. 2014 Jan;85(1):49-61
pubmed: 24284513
J Am Soc Nephrol. 2006 Jul;17(7):2034-47
pubmed: 16738019
Eur Rev Med Pharmacol Sci. 2014 Oct;18(19):2918-26
pubmed: 25339487
Leuk Res. 2014 Apr;38(4):490-5
pubmed: 24630365
J Hematol Oncol. 2016 Mar 05;9:18
pubmed: 26944254
J Thromb Haemost. 2013 Apr;11(4):627-33
pubmed: 23433091
Leuk Lymphoma. 2019 Feb;60(2):507-510
pubmed: 29966471
Br J Haematol. 2005 Feb;128(3):275-90
pubmed: 15667529
Int J Nephrol. 2016;2016:6232909
pubmed: 27974972
Case Rep Oncol Med. 2019 Sep 2;2019:5086963
pubmed: 31565452
Kidney Int. 2005 Aug;68(2):766-72
pubmed: 16014054
PLoS One. 2014 Mar 11;9(3):e90299
pubmed: 24618579
Semin Thromb Hemost. 2013 Jul;39(5):496-506
pubmed: 23633193
Haematologica. 2015 Oct;100(10):1267-74
pubmed: 26206796
Korean J Intern Med. 2018 Jul;33(4):790-797
pubmed: 28298076
Blood Adv. 2019 Jun 11;3(11):1729-1737
pubmed: 31175128
Blood. 2012 Aug 9;120(6):1197-201
pubmed: 22740446
Int J Hematol. 2020 Sep;112(3):377-384
pubmed: 32514928
Leuk Lymphoma. 2014 Jan;55(1):213-6
pubmed: 23607256
Curr Opin Nephrol Hypertens. 2006 Nov;15(6):610-6
pubmed: 17053476
Arch Intern Med. 2008 Nov 10;168(20):2212-8
pubmed: 19001197
J Am Soc Nephrol. 2021 Jan;32(1):138-150
pubmed: 32948670
Ann Hematol. 2020 Dec;99(12):2779-2785
pubmed: 32862283
Clin J Am Soc Nephrol. 2011 Oct;6(10):2452-61
pubmed: 21868617
Arch Intern Med. 2004 Mar 22;164(6):659-63
pubmed: 15037495
Blood. 2013 Sep 26;122(13):2176-84
pubmed: 23823316
Blood. 2020 May 7;135(19):1696-1703
pubmed: 32107559
Diabetologia. 2016 Aug;59(8):1624-7
pubmed: 27333885
J Am Soc Nephrol. 2008 Dec;19(12):2407-13
pubmed: 18799720
Front Cell Dev Biol. 2019 Dec 03;7:314
pubmed: 31850348
Curr Opin Nephrol Hypertens. 2015 Jan;24(1):88-95
pubmed: 25415616
Leuk Res. 2012 Nov;36(11):1387-92
pubmed: 22877729
Am J Hematol. 2009 Feb;84(2):102-8
pubmed: 19105233
Semin Thromb Hemost. 2013 Feb;39(1):101-11
pubmed: 23264112
Ann Hematol. 2019 Jul;98(7):1611-1616
pubmed: 31093708
Am J Hematol. 2020 Apr;95(4):379-386
pubmed: 31868244
Clin Nephrol. 2007 Dec;68(6):412-5
pubmed: 18184525