Severe Myocardial Dysfunction after Non-Ischemic Cardiac Arrest: Effectiveness of Percutaneous Assist Devices.
acute heart failure
cardiogenic shock
extracorporeal membrane oxygenation
left ventricular assist device
mechanical circulatory support
organ replacement therapies
physiopathology
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
17 Aug 2021
17 Aug 2021
Historique:
received:
30
06
2021
revised:
03
08
2021
accepted:
13
08
2021
entrez:
27
8
2021
pubmed:
28
8
2021
medline:
28
8
2021
Statut:
epublish
Résumé
Despite the improvements in standardized cardiopulmonary resuscitation, survival remains low, mainly due to initial myocardial dysfunction and hemodynamic instability. Our goal was to compare the efficacy of two left ventricular assist devices on resuscitation and hemodynamic supply in a porcine model of ventricular fibrillation (VF) cardiac arrest. Seventeen anaesthetized pigs had 12 min of untreated VF followed by 6 min of chest compression and boluses of epinephrine. Next, a first defibrillation was attempted and pigs were randomized to any of the three groups: control ( Only one of 5 pigs in the control group, 5 of 5 pigs in the Impella group, and 5 of 7 pigs in the ECMO group had ROSC ( Early mechanical circulatory support appeared to improve resuscitation rates in a shockable rhythm model of cardiac arrest. This approach appears promising and should be further evaluated.
Identifiants
pubmed: 34441919
pii: jcm10163623
doi: 10.3390/jcm10163623
pmc: PMC8396996
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : ABIOMED
ID : unrestricted
Références
Circulation. 2008 Dec 2;118(23):2452-83
pubmed: 18948368
Circulation. 2000 Aug 22;102(8 Suppl):I112-28
pubmed: 10966669
Circulation. 2000 Aug 22;102(8 Suppl):I1-11
pubmed: 10964901
J Trauma Acute Care Surg. 2013 Aug;75(2 Suppl 2):S173-7
pubmed: 23883904
Lancet. 2018 Mar 10;391(10124):980-988
pubmed: 29536862
Resuscitation. 2012 Nov;83(11):1397-403
pubmed: 22521449
Crit Care. 2015 Mar 26;19:123
pubmed: 25886909
Resuscitation. 1993 Feb;25(1):9-33
pubmed: 8446790
Eur Heart J Acute Cardiovasc Care. 2021 Jun 30;10(5):570-583
pubmed: 34057173
Crit Care Med. 2013 May;41(5):1186-96
pubmed: 23388518
Crit Care Med. 2010 Jan;38(1):254-60
pubmed: 19789452
Catheter Cardiovasc Interv. 2007 Oct 1;70(4):532-7
pubmed: 17896398
Crit Care. 2021 May 22;25(1):174
pubmed: 34022934
Circulation. 2000 Aug 22;102(8 Suppl):I166-71
pubmed: 10966672
Circulation. 1967 Jan;35(1):61-9
pubmed: 4289119
Lancet. 2008 Aug 16;372(9638):554-61
pubmed: 18603291
Resuscitation. 2010 Nov;81(11):1479-87
pubmed: 20828914
Ann Thorac Surg. 2014 Feb;97(2):610-6
pubmed: 24210621
JAMA. 2014 Jan 1;311(1):53-61
pubmed: 24240611
J Am Heart Assoc. 2016 Dec 22;5(12):
pubmed: 28007740
Intensive Care Med. 2016 May;42(5):750-752
pubmed: 26271905
Resuscitation. 2013 Nov;84(11):1525-9
pubmed: 23827888
N Engl J Med. 2001 Apr 26;344(17):1304-13
pubmed: 11320390
Circulation. 2013 Jul 23;128(4):328-36
pubmed: 23766351
J Am Coll Cardiol. 2015 May 19;65(19):e7-e26
pubmed: 25861963
Lancet. 1995 Aug 12;346(8972):417-21
pubmed: 7623574
J Am Coll Cardiol. 1996 Jul;28(1):232-40
pubmed: 8752819
Circulation. 2000 Aug 22;102(8 Suppl):I22-59
pubmed: 10966662
N Engl J Med. 2018 Aug 23;379(8):711-721
pubmed: 30021076
Lancet. 2020 Dec 5;396(10265):1807-1816
pubmed: 33197396
Resuscitation. 2017 Aug;117:109-117
pubmed: 28414164
Circ Cardiovasc Interv. 2010 Jun 1;3(3):200-7
pubmed: 20484098
Intensive Care Med. 2016 Dec;42(12):1922-1934
pubmed: 27647331
Crit Care. 2011;15(1):R29
pubmed: 21244674
Resuscitation. 2012 Aug;83(8):e177-8
pubmed: 22429977
J Clin Med. 2021 Jan 18;10(2):
pubmed: 33477532
Circulation. 2018 Mar 20;137(12):e67-e492
pubmed: 29386200
Resuscitation. 2013 May;84(5):609-15
pubmed: 23069592
Circulation. 2000 Aug 22;102(8 Suppl):I95-104
pubmed: 10966667
Resuscitation. 2018 Dec;133:194-206
pubmed: 30409433
Circulation. 2000 Aug 22;102(8 Suppl):I129-35
pubmed: 10966670
Resuscitation. 2006 Sep;70(3):404-9
pubmed: 16828952
N Engl J Med. 2003 Jun 26;348(26):2626-33
pubmed: 12826637
Resuscitation. 2018 Mar;124:43-48
pubmed: 29305926
Resuscitation. 2012 Nov;83(11):1343-8
pubmed: 22824170