Association of Skin Microbiome with the Onset and Recurrence of Pressure Injury in Bedridden Elderly People.
Staphylococcus
bedridden elderly
infection
pressure injury
skin microbiome
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
27 Jul 2021
27 Jul 2021
Historique:
received:
07
06
2021
revised:
14
07
2021
accepted:
23
07
2021
entrez:
27
8
2021
pubmed:
28
8
2021
medline:
28
8
2021
Statut:
epublish
Résumé
Pressure injuries have been identified as one of the main health hazards among bedridden elderly people. Bedridden elderly people often stay in the same position for a long time, because they cannot switch positions; thus, the blood flow in the part of the body that is being compressed between the bed and their own weight is continuously blocked. As a result, redness and ulcers occur due to lacking oxygen and nutrients in the skin tissues, and these sites are often infected with microorganisms and, thus, become suppurative wounds, a condition commonly determined as pressure injuries. If left untreated, the pressure injury will recur with microbial infections, often resulting in cellulitis, osteomyelitis, and sepsis. The skin microbiome, in which many types of bacteria coexist, is formed on the skin surface. However, it remains unclear what characteristic of the skin microbiome among the bedridden elderly constitutes the development and severity of pressure injuries and the development of post-pressure injury infections. Thus, in this review article, we outlined the changes in the skin microbiome among the bedridden elderly people and their potential involvement in the onset and recurrence of pressure injuries.
Identifiants
pubmed: 34442680
pii: microorganisms9081603
doi: 10.3390/microorganisms9081603
pmc: PMC8400065
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Japan Society for the Promotion of Science
ID : 17H04428, 21H03221, 20H03960
Organisme : Kanazawa University
ID : Sakigake Project
Références
J Clin Microbiol. 2003 Jan;41(1):295-303
pubmed: 12517864
Infect Immun. 2009 Jun;77(6):2367-75
pubmed: 19307217
Ostomy Wound Manage. 2003 Jan;49(1):44-53
pubmed: 12532033
Sci Transl Med. 2017 Jul 5;9(397):
pubmed: 28679656
Genome Res. 2015 Oct;25(10):1514-20
pubmed: 26430162
PLoS One. 2015 Sep 25;10(9):e0138117
pubmed: 26407180
J Gen Microbiol. 1984 Apr;130(4):803-7
pubmed: 6234376
J Tissue Viability. 2008 Aug;17(3):76-81
pubmed: 18722313
Crit Care Nurse. 2013 Dec;33(6):57-66
pubmed: 24293556
BMC Microbiol. 2015 Mar 21;15:66
pubmed: 25880246
Ont Health Technol Assess Ser. 2009;9(3):1-203
pubmed: 23074533
Curr Probl Dermatol. 2018;54:132-142
pubmed: 30130782
Int J Dermatol. 2017 Jul;56(7):762-766
pubmed: 28369843
Int J Med Microbiol. 2014 Jan;304(1):63-71
pubmed: 24119540
J Invest Dermatol. 2009 Jul;129(7):1824-35
pubmed: 19177139
J Invest Dermatol. 1978 Dec;71(6):378-81
pubmed: 31403
Biol Res Nurs. 2021 Jan;23(1):75-81
pubmed: 32648469
Nat Rev Microbiol. 2018 Mar;16(3):143-155
pubmed: 29332945
Nature. 2012 Jun 13;486(7402):207-14
pubmed: 22699609
Clin Orthop Relat Res. 1975 Oct;(112):89-100
pubmed: 1192654
An Bras Dermatol. 2016 Sep-Oct;91(5):676-678
pubmed: 27828651
Clin Exp Dermatol. 2016 Oct;41(7):818-20
pubmed: 27663163
J Invest Dermatol. 2012 Mar;132(3 Pt 2):933-9
pubmed: 22189793
J Invest Dermatol. 2008 Jan;128(1):79-86
pubmed: 17671515
J Dermatol Sci. 2015 Aug;79(2):119-26
pubmed: 26012780
J Invest Dermatol. 2013 Sep;133(9):2152-60
pubmed: 23337890
J Invest Dermatol. 2010 Feb;130(2):529-40
pubmed: 19710689
J Hosp Infect. 2013 Apr;83(4):314-20
pubmed: 23313027
Science. 2009 May 29;324(5931):1190-2
pubmed: 19478181
J Am Acad Dermatol. 2013 Jul;69(1):143-55
pubmed: 23489584
Acta Derm Venereol. 1990;70(5):429-31
pubmed: 1980979
Wound Repair Regen. 2011 Jan-Feb;19(1):10-8
pubmed: 21134034
J Gen Microbiol. 1981 Jun;124(2):393-401
pubmed: 7035615
APMIS. 1996 Dec;104(12):895-9
pubmed: 9048868
Int Wound J. 2018 Apr;15(2):225-236
pubmed: 29243356
Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4554-61
pubmed: 20847294
PLoS One. 2012;7(3):e33865
pubmed: 22457796
Appl Environ Microbiol. 2009 Dec;75(23):7537-41
pubmed: 19801464
J Wound Ostomy Continence Nurs. 2016 Nov/Dec;43(6):585-597
pubmed: 27749790
Eur J Clin Microbiol Infect Dis. 2018 May;37(5):969-975
pubmed: 29479635
BMC Microbiol. 2017 Jan 21;17(1):23
pubmed: 28109256
Annu Rev Microbiol. 1988;42:441-64
pubmed: 3144238
PLoS Biol. 2008 Nov 18;6(11):e280
pubmed: 19018661
Curr Opin Allergy Clin Immunol. 2019 Aug;19(4):328-333
pubmed: 31107258
J Clin Nurs. 2011 Sep;20(17-18):2633-44
pubmed: 21702861
An Bras Dermatol. 2020 Mar - Apr;95(2):187-193
pubmed: 32113677
Science. 2014 Nov 21;346(6212):954-9
pubmed: 25414304
Nat Microbiol. 2016 Jul 11;1(9):16106
pubmed: 27562258
Immunity. 2015 Apr 21;42(4):756-66
pubmed: 25902485
PLoS One. 2015 Oct 28;10(10):e0141842
pubmed: 26510185
Clin Microbiol Rev. 2001 Apr;14(2):244-69
pubmed: 11292638
mSphere. 2017 Sep 13;2(5):
pubmed: 28932812
Trends Microbiol. 2013 Dec;21(12):660-8
pubmed: 24238601
Cell. 2016 May 5;165(4):854-66
pubmed: 27153496
J Enterostomal Ther. 1988 Jan-Feb;15(1):4-17
pubmed: 3339152
J Steroid Biochem Mol Biol. 2003 Dec;87(4-5):327-36
pubmed: 14698214
Front Microbiol. 2018 Oct 02;9:2362
pubmed: 30333815
J Biol Chem. 2008 Jul 25;283(30):20645-52
pubmed: 18515361
Can J Microbiol. 1984 May;30(5):647-52
pubmed: 6744125
Cochrane Database Syst Rev. 2016 Apr 04;4:CD011586
pubmed: 27040598
Indian J Dermatol Venereol Leprol. 2017 Sep-Oct;83(5):610-611
pubmed: 28749385
Drug Discov Today Dis Mech. 2013 Dec 1;10(3-4):
pubmed: 24273587
J Wound Care. 2020 Apr 1;29(Sup4):S14-S24
pubmed: 32279614
Diagn Microbiol Infect Dis. 1986 May;5(1):31-8
pubmed: 3709093
JAMA. 2006 Aug 23;296(8):1020
pubmed: 16926361
Int J Cosmet Sci. 2006 Oct;28(5):359-70
pubmed: 18489300
J Invest Dermatol. 2016 May;136(5):947-956
pubmed: 26829039
Wound Repair Regen. 2007 Jan-Feb;15(1):17-22
pubmed: 17244315
Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2927-32
pubmed: 17293459
J Spinal Cord Med. 2015 Mar;38(2):147-60
pubmed: 25130374
J Eur Acad Dermatol Venereol. 2020 May;34(5):1043-1049
pubmed: 31713895
J Wound Care. 2008 Aug;17(8):333-41
pubmed: 18754194
mBio. 2013 Apr 30;4(3):e00003-13
pubmed: 23631911
Am J Infect Control. 2008 Jun;36(5):309-32
pubmed: 18538699
Curr Probl Dermatol. 2018;54:87-94
pubmed: 30130777
BMC Res Notes. 2016 Jul 26;9:365
pubmed: 27456340
Ostomy Wound Manage. 2011 Feb;57(2):24-37
pubmed: 21350270
Ostomy Wound Manage. 2005 Jan;51(1):50-9
pubmed: 15695835
Clin Infect Dis. 1993 Jun;16 Suppl 4:S175-80
pubmed: 8324114
J Med Microbiol. 2005 Dec;54(Pt 12):1231-1238
pubmed: 16278439
Nat Rev Microbiol. 2011 Apr;9(4):244-53
pubmed: 21407241
Science. 2009 Dec 18;326(5960):1694-7
pubmed: 19892944
Biol Res Nurs. 2021 Jan;23(1):82-90
pubmed: 32696660
Front Med (Lausanne). 2020 Apr 08;7:101
pubmed: 32322583
Genome Res. 2012 May;22(5):850-9
pubmed: 22310478
J Invest Dermatol. 1971 Feb;56(2):127-31
pubmed: 4997367
Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3801-9
pubmed: 27286824
Sci Rep. 2020 Apr 6;10(1):5963
pubmed: 32249804
Nat Methods. 2010 May;7(5):335-6
pubmed: 20383131
Am J Clin Dermatol. 2020 Sep;21(Suppl 1):25-35
pubmed: 32914214
Iran J Parasitol. 2019 Jul-Sep;14(3):459-464
pubmed: 31673265
Benef Microbes. 2014 Jun 1;5(2):201-15
pubmed: 24322878
J Wound Ostomy Continence Nurs. 2008 Nov-Dec;35(6):571-7
pubmed: 19018196
J Invest Dermatol. 2008 May;128(5):1329-31
pubmed: 17960173
Am J Med. 1984 May 15;76(5A):172-9
pubmed: 6372467
Semin Immunopathol. 2007 Apr;29(1):3-14
pubmed: 17621950
J Biol Chem. 2003 Feb 21;278(8):5718-27
pubmed: 12468539
J Wound Care. 1996 Jun;5(6):277-80
pubmed: 8850916