Sperm Lipid Markers of Male Fertility in Mammals.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
16 Aug 2021
Historique:
received: 29 06 2021
revised: 10 08 2021
accepted: 12 08 2021
entrez: 27 8 2021
pubmed: 28 8 2021
medline: 14 9 2021
Statut: epublish

Résumé

Sperm plasma membrane lipids are essential for the function and integrity of mammalian spermatozoa. Various lipid types are involved in each key step within the fertilization process in their own yet coordinated way. The balance between lipid metabolism is tightly regulated to ensure physiological cellular processes, especially referring to crucial steps such as sperm motility, capacitation, acrosome reaction or fusion. At the same time, it has been shown that male reproductive function depends on the homeostasis of sperm lipids. Here, we review the effects of phospholipid, neutral lipid and glycolipid homeostasis on sperm fertilization function and male fertility in mammals.

Identifiants

pubmed: 34445473
pii: ijms22168767
doi: 10.3390/ijms22168767
pmc: PMC8395862
pii:
doi:

Substances chimiques

Biomarkers 0
Membrane Lipids 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Shuwen Shan (S)

Institute of Veterinary Medicine, Faculty of Agricultural Sciences, Georg-August-University of Goettingen, 37077 Göttingen, Germany.

Fangzheng Xu (F)

Institute of Veterinary Medicine, Faculty of Agricultural Sciences, Georg-August-University of Goettingen, 37077 Göttingen, Germany.

Marc Hirschfeld (M)

Institute of Veterinary Medicine, Faculty of Agricultural Sciences, Georg-August-University of Goettingen, 37077 Göttingen, Germany.

Bertram Brenig (B)

Institute of Veterinary Medicine, Faculty of Agricultural Sciences, Georg-August-University of Goettingen, 37077 Göttingen, Germany.

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