Mitochondrial dysfunction and oxidative stress in liver of male albino rats after exposing to sub-chronic intoxication of chlorpyrifos, cypermethrin, and imidacloprid.

Animals Antioxidants / metabolism Chlorpyrifos / metabolism Insecticides / metabolism Liver / metabolism Mitochondria Neonicotinoids Nitro Compounds Oxidative Stress Protein Carbonylation Pyrethrins Rats
HPLC analysis Histological analysis Insecticides Mitochondria Oxidative stress Rat liver

Journal

Pesticide biochemistry and physiology
ISSN: 1095-9939
Titre abrégé: Pestic Biochem Physiol
Pays: United States
ID NLM: 1301573

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 03 06 2021
revised: 08 07 2021
accepted: 14 07 2021
entrez: 27 8 2021
pubmed: 28 8 2021
medline: 1 9 2021
Statut: ppublish

Résumé

The adverse effects of chlorpyrifos, cypermethrin, and imidacloprid on mitochondrial dysfunction and oxidative stress biomarkers were studied in rat liver. The liver deficiency was also confirmed by histological analysis and gel electrophoresis. Each insecticide was administered orally with five doses per week for 28 days to male albino rats at 1/50 of the LD

Identifiants

DOI: 10.1016/j.pestbp.2021.104938 PMID: 34446205
pubmed: 34446205
pii: S0048-3575(21)00169-3
doi: 10.1016/j.pestbp.2021.104938
pii:
doi:

Substances chimiques

Antioxidants 0
Insecticides 0
Neonicotinoids 0
Nitro Compounds 0
Pyrethrins 0
cypermethrin 1TR49121NP
imidacloprid 3BN7M937V8
Chlorpyrifos JCS58I644W

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104938

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Mostafa A I Taha (MAI)

Department of Pesticide Chemistry and Technology, Laboratory of Bioenergetics and Membrane Toxicology, Faculty of Agriculture, 21545-El-Shatby, Alexandria University, Alexandria, Egypt.

Mohamed E I Badawy (MEI)

Department of Pesticide Chemistry and Technology, Laboratory of Pesticide Residues Analysis, Faculty of Agriculture, 21545-El-Shatby, Alexandria University, Alexandria, Egypt. Electronic address: mohamed.badawy@alexu.edu.eg.

Reda K Abdel-Razik (RK)

Mammalian Toxicology Department, Central Agricultural Pesticide Laboratory, Agricultural Research Center, 21616-El-Sabahia, Alexandria, Egypt.

Hassan M Younis (HM)

Department of Pesticide Chemistry and Technology, Laboratory of Bioenergetics and Membrane Toxicology, Faculty of Agriculture, 21545-El-Shatby, Alexandria University, Alexandria, Egypt.

Mahmoud M Abo-El-Saad (MM)

Department of Pesticide Chemistry and Technology, Laboratory of Bioenergetics and Membrane Toxicology, Faculty of Agriculture, 21545-El-Shatby, Alexandria University, Alexandria, Egypt.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Composés organothiophosphorés › Organothiophosphates › Chlorpyriphos › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Pesticides › Insecticides › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Système digestif › Foie › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Mitochondries › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Néonicotinoïdes › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Composés chimiques organiques › Composés nitrés › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Carbonylation des protéines › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Monoterpènes › Cyclopentane monoterpenes › Pyréthrines › Mitochondrial dysfunction and oxidative stress...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Mitochondrial dysfunction and oxidative stress...