Enhanced pyrethroid potency in Drosophila melanogaster expressing voltage-gated potassium channel mutants: Insecticidal activity and neuronal action.

Animals Drosophila melanogaster / genetics Insecticides / toxicity Permethrin Potassium Channels, Voltage-Gated / genetics Pyrethrins / toxicity
2-methoxy-N-((1-phenylcyclopentyl)methyl)benzamide 4-aminopyridine Deltamethrin Permethrin Synergism

Journal

Pesticide biochemistry and physiology
ISSN: 1095-9939
Titre abrégé: Pestic Biochem Physiol
Pays: United States
ID NLM: 1301573

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 06 04 2021
revised: 19 07 2021
accepted: 20 07 2021
entrez: 27 8 2021
pubmed: 28 8 2021
medline: 1 9 2021
Statut: ppublish

Résumé

Previous studies have shown that blockers of voltage-gated potassium (Kv) channels, such as 4-aminopyridine (4-AP) and 2-methoxy-N-((1-phenylcyclopentyl)methyl)benzamide (2-MPB) synergized pyrethroid toxicity as well, or better than, piperonyl butoxide. The present study assessed the involvement of different Kv channels as possible pyrethroid synergist targets in Drosophila melanogaster. Three Kv1 mutants (Sh

Identifiants

DOI: 10.1016/j.pestbp.2021.104940 PMID: 34446207
pubmed: 34446207
pii: S0048-3575(21)00171-1
doi: 10.1016/j.pestbp.2021.104940
pii:
doi:

Substances chimiques

Insecticides 0
Potassium Channels, Voltage-Gated 0
Pyrethrins 0
Permethrin 509F88P9SZ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104940

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Shiyao Jiang (S)

Emerging Pathogens Institute, Entomology and Nematology Department, University of Florida, Gainesville, FL, USA. Electronic address: Shiyao.jiang@syngenta.com.

Jeffrey R Bloomquist (JR)

Emerging Pathogens Institute, Entomology and Nematology Department, University of Florida, Gainesville, FL, USA. Electronic address: jbquist@epi.ufl.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Enhanced pyrethroid potency in Drosophila...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › Enhanced pyrethroid potency in Drosophila...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Pesticides › Insecticides › Enhanced pyrethroid potency in Drosophila...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Monoterpènes › Cyclopentane monoterpenes › Pyréthrines › Perméthrine › Enhanced pyrethroid potency in Drosophila...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques voltage-dépendants › Enhanced pyrethroid potency in Drosophila...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Monoterpènes › Cyclopentane monoterpenes › Pyréthrines › Enhanced pyrethroid potency in Drosophila...