Supplementation of Diets With Bovine Colostrum Influences Immune and Gut Function in Kittens.
GALT
bovine colostrum
gut health
gut microflora
gut-associated lymphoid tissue
nutritional immunology
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2021
2021
Historique:
received:
04
03
2021
accepted:
15
07
2021
entrez:
27
8
2021
pubmed:
28
8
2021
medline:
28
8
2021
Statut:
epublish
Résumé
In its early life a kitten faces many significant events including separation from its mother, re-homing and vaccination. The kitten is also slowly adapting to their post-weaning diet. Recent advances in companion animal nutrition have indicated that functional ingredients such as colostrum can help support the immune system and gastrointestinal health. Here we report for the first time the effect of feeding a diet containing 0.1% spray dried bovine colostrum (BC) to growing kittens on gut-associated lymphoid (GALT) tissue responses, systemic immune responses, and on intestinal microbiota stability. BC supplementation induced increased faecal IgA expression, and a faster and stronger antibody response to a rabies vaccine booster, indicative of better localised and systemic immune function, respectively. BC supplementation also helped to maintain kittens' intestinal microbiota stability in the face of a mildly challenging life event. These results show that BC supplementation can help strengthen the immune system and enhance the gut microbiota stability of growing kittens.
Identifiants
pubmed: 34447799
doi: 10.3389/fvets.2021.675712
pmc: PMC8383104
doi:
Types de publication
Journal Article
Langues
eng
Pagination
675712Informations de copyright
Copyright © 2021 Gore, Satyaraj, Labuda, Engler, Sun, Kerr and Conboy-Schmidt.
Déclaration de conflit d'intérêts
All authors are employees of Nestlé Purina Research.
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