Synthetic modifications of abietane diterpene acids to potent antimicrobial agents.

Humans Abietanes / pharmacology Methicillin-Resistant Staphylococcus aureus HEK293 Cells Anti-Infective Agents / pharmacology Antifungal Agents / pharmacology Cryptococcus neoformans Mycobacterium tuberculosis Microbial Sensitivity Tests Anti-Bacterial Agents / pharmacology
Dihydroquinopimaric acid M. tuberculosis H37Rv antifungal activity antimicrobial activity antitubercular activity docking studies maleopimaric acid

Journal

Natural product research
ISSN: 1478-6427
Titre abrégé: Nat Prod Res
Pays: England
ID NLM: 101167924

Informations de publication

Date de publication:
Jan 2023
Historique:
pubmed: 28 8 2021
medline: 10 1 2023
entrez: 27 8 2021
Statut: ppublish

Résumé

Among abietane type semisynthetic diterpenoids, a series of quinopimaric and maleopimaric acid derivatives modified at the carboxyl and carbonyl groups, and in ring

Identifiants

DOI: 10.1080/14786419.2021.1969566 PMID: 34448419
pubmed: 34448419
doi: 10.1080/14786419.2021.1969566
doi:

Substances chimiques

Abietanes 0
Anti-Infective Agents 0
Antifungal Agents 0
Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

313-321

Auteurs

Irina E Smirnova (IE)

Ufa Institute of Chemistry of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation.
ORCID: 0000-0001-7176-505X

Elena V Tret'yakova (EV)

Ufa Institute of Chemistry of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation.

Dmitry S Baev (DS)

N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation.

Oxana B Kazakova (OB)

Ufa Institute of Chemistry of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation.
ORCID: 0000-0002-5606-1588

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Diterpènes de type abiétane › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antifongiques › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Cryptococcus › Cryptococcus neoformans › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Synthetic modifications of abietane diterpene...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Synthetic modifications of abietane diterpene...