Formulation and Characterization of a New Injectable Bone Substitute Composed PVA/Borax/CaCO
bone graft
bone tissue engineering
bone tissue regeneration
fracture
injectable
osteoblast
Journal
Journal of functional biomaterials
ISSN: 2079-4983
Titre abrégé: J Funct Biomater
Pays: Switzerland
ID NLM: 101570734
Informations de publication
Date de publication:
11 Aug 2021
11 Aug 2021
Historique:
received:
17
06
2021
revised:
30
07
2021
accepted:
04
08
2021
entrez:
27
8
2021
pubmed:
28
8
2021
medline:
28
8
2021
Statut:
epublish
Résumé
The occurrence of bone-related disorders and diseases has dramatically increased in recent years around the world. Demineralized bone matrix (DBM) has been widely used as a bone implant due to its osteoinduction and bioactivity. However, the use of DBM is limited because it is a particulate material, which makes it difficult to manipulate and implant with precision. In addition, these particles are susceptible to migration to other sites. To address this situation, DBM is commonly incorporated into a variety of carriers. An injectable scaffold has advantages over bone grafts or preformed scaffolds, such as the ability to flow and fill a bone defect. The aim of this research was to develop a DBM carrier with such viscoelastic properties in order to obtain an injectable bone substitute (IBS). The developed DBM carrier consisted of a PVA/glycerol network cross-linked with borax and reinforced with CaCO
Identifiants
pubmed: 34449632
pii: jfb12030046
doi: 10.3390/jfb12030046
pmc: PMC8395841
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)
ID : 133377757790
Références
Int J Biol Macromol. 2018 Jul 15;114:1026-1032
pubmed: 29578008
Int J Biol Macromol. 2021 Mar 1;172:66-73
pubmed: 33434549
J Mech Behav Biomed Mater. 2017 May;69:355-361
pubmed: 28161689
Adv Drug Deliv Rev. 2007 May 30;59(4-5):263-73
pubmed: 17507111
Biomaterials. 2005 May;26(13):1553-63
pubmed: 15522757
Mater Sci Eng C Mater Biol Appl. 2021 Jan;120:111677
pubmed: 33545839
Int J Biol Macromol. 2019 May 15;129:936-943
pubmed: 30738162
Acta Biomater. 2012 Feb;8(2):753-62
pubmed: 22079781
Mater Sci Eng C Mater Biol Appl. 2015 May;50:257-65
pubmed: 25746269
PLoS One. 2017 May 25;12(5):e0178158
pubmed: 28542453
J Biomed Mater Res B Appl Biomater. 2009 Apr;89(1):127-34
pubmed: 18780340
Mater Sci Eng C Mater Biol Appl. 2020 May;110:110685
pubmed: 32204113
Sci Rep. 2018 Jan 24;8(1):1531
pubmed: 29367754
Mater Sci Eng C Mater Biol Appl. 2018 Sep 1;90:365-378
pubmed: 29853102
J Tissue Eng. 2019 May 02;10:2041731419845852
pubmed: 31105928
Mater Sci Eng C Mater Biol Appl. 2019 Mar;96:955-967
pubmed: 30606607
Eur Cell Mater. 2011 May 15;21:407-29; discussion 429
pubmed: 21604242
Adv Drug Deliv Rev. 2002 Jan 17;54(1):13-36
pubmed: 11755704
Mater Sci Eng C Mater Biol Appl. 2021 May;124:112065
pubmed: 33947558
J Biomed Mater Res A. 2003 Dec 15;67(4):1329-37
pubmed: 14624520
Cell Tissue Bank. 2005;6(1):3-12
pubmed: 15735896
Acta Biomater. 2016 Feb;31:326-338
pubmed: 26631875
Biomaterials. 2006 May;27(15):2907-15
pubmed: 16448693
Molecules. 2016 Nov 21;21(11):
pubmed: 27879635
J Orthop Res. 2003 Jul;21(4):648-54
pubmed: 12798064
Front Microbiol. 2017 Apr 13;8:675
pubmed: 28450860
J Mech Behav Biomed Mater. 2015 Aug;48:38-45
pubmed: 25913606
Clin Chim Acta. 2020 Nov;510:544-555
pubmed: 32798511
Biomacromolecules. 2016 Dec 12;17(12):3862-3871
pubmed: 27775890
Addit Manuf. 2021 Mar;39:
pubmed: 34307059
Biomaterials. 2003 May;24(12):2037-43
pubmed: 12628823
Chem Soc Rev. 2012 Mar 21;41(6):2193-221
pubmed: 22116474
J Cell Physiol. 2018 Dec;233(12):9777-9785
pubmed: 30078218
J Colloid Interface Sci. 2019 Feb 15;536:224-234
pubmed: 30368094
Acta Biomater. 2019 Jan 1;83:425-434
pubmed: 30342285
Calcif Tissue Int. 2014 Aug;95(2):183-93
pubmed: 24916279
Bioact Mater. 2018 May 28;3(4):389-400
pubmed: 30003178
Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19590-5
pubmed: 23150549
Acta Biomater. 2017 Mar 1;50:1-19
pubmed: 27838464
Regul Toxicol Pharmacol. 2021 Apr;121:104873
pubmed: 33485927
ACS Appl Mater Interfaces. 2019 Mar 6;11(9):8749-8762
pubmed: 30734555
Tissue Eng Part B Rev. 2008 Jun;14(2):179-86
pubmed: 18544015
Des Monomers Polym. 2017 Sep 29;20(1):505-513
pubmed: 29491822
Acta Biomater. 2014 Nov;10(11):4574-4582
pubmed: 25046637
Int J Biol Macromol. 2019 Sep 1;136:1247-1257
pubmed: 31247228
Mater Sci Eng C Mater Biol Appl. 2016 Feb;59:948-957
pubmed: 26652452
J Chromatogr A. 2020 Aug 2;1624:461260
pubmed: 32540085
Chem Commun (Camb). 2016 May 19;52(43):7036-8
pubmed: 27161807
Organogenesis. 2012 Oct-Dec;8(4):114-24
pubmed: 23247591
J Biomed Mater Res. 1993 Jan;27(1):35-45
pubmed: 8380597
J Mater Sci Mater Med. 2010 Jun;21(6):1867-74
pubmed: 20333539
J Orthop Res. 2000 May;18(3):503-11
pubmed: 10937641
Int J Biomater. 2019 Jun 25;2019:7179243
pubmed: 31341479
Colloids Surf B Biointerfaces. 2020 Feb;186:110720
pubmed: 31855688
Mater Sci Eng C Mater Biol Appl. 2016 Feb;59:818-827
pubmed: 26652437