NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia.
Notch
endoplasmic reticulum stress
expansion
gene therapy
hematopoietic stem cell
hypoxia
pathways
signaling
transplantation
Journal
Stem cell reports
ISSN: 2213-6711
Titre abrégé: Stem Cell Reports
Pays: United States
ID NLM: 101611300
Informations de publication
Date de publication:
14 09 2021
14 09 2021
Historique:
received:
11
12
2020
revised:
30
07
2021
accepted:
01
08
2021
pubmed:
28
8
2021
medline:
11
3
2022
entrez:
27
8
2021
Statut:
ppublish
Résumé
Activation of NOTCH signaling in human hematopoietic stem/progenitor cells (HSPCs) by treatment with an engineered Delta-like ligand (DELTA1
Identifiants
pubmed: 34450041
pii: S2213-6711(21)00390-8
doi: 10.1016/j.stemcr.2021.08.001
pmc: PMC8452537
pii:
doi:
Substances chimiques
Antigens, CD34
0
Biomarkers
0
Receptors, Notch
0
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
2336-2350Subventions
Organisme : Intramural NIH HHS
ID : Z99 HL999999
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA HL006218
Pays : United States
Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.
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