Long-Term Follow-Up of Gemogenovatucel-T (Vigil) Survival and Molecular Signals of Immune Response in Recurrent Ovarian Cancer.

NanoString TIS Vigil gene expression profile immune response immunotherapy ovarian cancer

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
12 Aug 2021
Historique:
received: 14 06 2021
revised: 03 08 2021
accepted: 06 08 2021
entrez: 28 8 2021
pubmed: 29 8 2021
medline: 29 8 2021
Statut: epublish

Résumé

To determine the relationship between gene expression profile (GEP) and overall survival (OS) by NanoString following treatment with Vigil. Recurrent ovarian cancer patients ( GEP stratified by TIS Vigil demonstrates OS benefit in correlation with TIS

Identifiants

pubmed: 34452019
pii: vaccines9080894
doi: 10.3390/vaccines9080894
pmc: PMC8402348
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Rodney P Rocconi (RP)

Mitchell Cancer Institute, Division of Gynecologic Oncology, University of South Alabama, Mobile, AL 36604, USA.

Laura Stanbery (L)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Luciana Madeira da Silva (L)

Department of Microbiology and Immunology, University of South Alabama, Mobile, AL 36688, USA.

Robert A Barrington (RA)

Department of Microbiology and Immunology, University of South Alabama, Mobile, AL 36688, USA.

Phylicia Aaron (P)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Luisa Manning (L)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Staci Horvath (S)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Gladice Wallraven (G)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Ernest Bognar (E)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Adam Walter (A)

Promedica, Sylvania, OH 43560, USA.

John Nemunaitis (J)

Gradalis, Inc., 2545 Golden Bear Drive, Suite 110, Carrollton, TX 75006, USA.

Classifications MeSH