How does the convergence of prematurity and congenital heart disease impact the developing brain?
Brain injury
Congenital heart defects
Magnetic resonance imaging
Preterm
Journal
Seminars in perinatology
ISSN: 1558-075X
Titre abrégé: Semin Perinatol
Pays: United States
ID NLM: 7801132
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
pubmed:
29
8
2021
medline:
15
12
2021
entrez:
28
8
2021
Statut:
ppublish
Résumé
Prematurity and congenital heart disease (CHD) are individually associated with increased risk of brain injury and adverse neurodevelopmental outcomes. Delayed brain development in newborns with CHD has been documented to begin in utero and predisposes newborns with CHD to brain injury. Little is known about the combined risks when prematurity and CHD co-occur. The purpose of this review is to highlight the unique vulnerability of preterm newborns with CHD to brain dysmaturation and brain injury, and the urgent need for prospective research.
Identifiants
pubmed: 34452752
pii: S0146-0005(21)00086-0
doi: 10.1016/j.semperi.2021.151472
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
151472Subventions
Organisme : NINDS NIH HHS
ID : P01 NS082330
Pays : United States
Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have no conflicts of interest to disclose. The manuscript is supported by work funded by the National Institutes of HealthP01NS082330 [PM].