The effect of Origanum majorana tea on motor and non-motor symptoms in patients with idiopathic Parkinson's disease: A randomized controlled pilot study.


Journal

Parkinsonism & related disorders
ISSN: 1873-5126
Titre abrégé: Parkinsonism Relat Disord
Pays: England
ID NLM: 9513583

Informations de publication

Date de publication:
10 2021
Historique:
received: 31 03 2021
revised: 16 08 2021
accepted: 22 08 2021
pubmed: 30 8 2021
medline: 9 2 2022
entrez: 29 8 2021
Statut: ppublish

Résumé

The effect of Origanum majorana tea consumption on motor and non-motor symptoms was investigated in patients with idiopathic Parkinson's disease, measured by validated tools. Sixty patients with idiopathic Parkinson's disease and under conventional medication were enrolled voluntarily in the study. All participants were randomized on double-blind to placebo or Origanum majorana. Clinical assessment with validated tools (UPDRSIII, NMSS, and BDI) was done before Origanum majorana or placebo consumption (Day 0) and at the end of the experiment (Day 30). The treatment groups were similar at baseline on demographic and clinical variables. During the course of study, nine participants withdrew for reasons of noncompliance and inability to follow-up. Fifty-one participants completed the study. Upon completion of 30 days of treatment, Origanum majorana tea consumption did not decrease the UPDRSIII score ([UPDRSIII

Identifiants

pubmed: 34455218
pii: S1353-8020(21)00307-2
doi: 10.1016/j.parkreldis.2021.08.013
pii:
doi:

Substances chimiques

Tea 0

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

23-27

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Chbili Chahra (C)

Metabolic Biophysics and Applied Pharmacology Laboratory, Faculty of Medicine Ibn El Jazzar Sousse, Sousse University, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia. Electronic address: chahrachbili@yahoo.fr.

Hassine Anis (H)

Neurology Department, Sahloul Teaching Hospital, Sousse, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Douma Bissene (D)

Neurology Department, Sahloul Teaching Hospital, Sousse, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Selmi Mejda (S)

Metabolic Biophysics and Applied Pharmacology Laboratory, Faculty of Medicine Ibn El Jazzar Sousse, Sousse University, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Maatoug Jihène (M)

Department of Epidemiology, University Hospital Farhat Hached, Sousse, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Naija Salma (N)

Neurology Department, Sahloul Teaching Hospital, Sousse, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Nouira Manel (N)

Metabolic Biophysics and Applied Pharmacology Laboratory, Faculty of Medicine Ibn El Jazzar Sousse, Sousse University, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Ben Amor Sana (BA)

Neurology Department, Sahloul Teaching Hospital, Sousse, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Khairi Hedi (K)

University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

Ben Fredj Maha (BF)

Metabolic Biophysics and Applied Pharmacology Laboratory, Faculty of Medicine Ibn El Jazzar Sousse, Sousse University, Tunisia; University of Sousse, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia.

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Classifications MeSH