Myelin basic protein expression in thymoma after methylprednisolone administration for multiple sclerosis.
autoimmune disease
multiple sclerosis
thymoma
thymus
video‐assisted thoracoscopic thymectomy
Journal
Respirology case reports
ISSN: 2051-3380
Titre abrégé: Respirol Case Rep
Pays: United States
ID NLM: 101631052
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
15
07
2021
accepted:
06
08
2021
entrez:
30
8
2021
pubmed:
31
8
2021
medline:
31
8
2021
Statut:
epublish
Résumé
The relationship between thymic epithelial tumour and demyelinating disease (DD) is unknown and surgical resection has not been optimized. A 39-year-old woman was administrated methylprednisolone for newly diagnosed multiple sclerosis. A thymic tumour was found in the antero-superior mediastinum via computed tomography of the chest. Video-assisted thoracoscopic thymectomy was performed. Histologically, the tumour was diagnosed as Type AB thymoma. Immunohistochemical staining showed positive myelin basic protein (MBP) in the cytosol of spindle cells in the tumour specimen. Germinal centres or lymphocytes infiltration were not noted. Ectopic MBP presentation in thymoma might be correlated with DD.
Identifiants
pubmed: 34457311
doi: 10.1002/rcr2.834
pii: RCR2834
pmc: PMC8374605
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e0834Informations de copyright
© 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
Déclaration de conflit d'intérêts
None declared.
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