miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine.
CORT
Dendrite morphology
Ketamine
REST
Stress
miR-9-5p
Journal
Neurobiology of stress
ISSN: 2352-2895
Titre abrégé: Neurobiol Stress
Pays: United States
ID NLM: 101643409
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
13
05
2021
revised:
03
08
2021
accepted:
07
08
2021
entrez:
30
8
2021
pubmed:
31
8
2021
medline:
31
8
2021
Statut:
epublish
Résumé
Converging clinical and preclinical evidence demonstrates that depressive phenotypes are associated with synaptic dysfunction and dendritic simplification in cortico-limbic glutamatergic areas. On the other hand, the rapid antidepressant effect of acute ketamine is consistently reported to occur together with the rescue of dendritic atrophy and reduction of spine number induced by chronic stress in the hippocampus and prefrontal cortex of animal models of depression. Nevertheless, the molecular mechanisms underlying these morphological alterations remain largely unknown. Here, we found that miR-9-5p levels were selectively reduced in the hippocampus of rats vulnerable to Chronic Mild Stress (CMS), while acute subanesthetic ketamine restored its levels to basal condition in just 24h; miR-9-5p expression inversely correlated with the anhedonic phenotype. A decrease of miR-9-5p was reproduced in an
Identifiants
pubmed: 34458512
doi: 10.1016/j.ynstr.2021.100381
pii: S2352-2895(21)00089-8
pmc: PMC8379501
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100381Informations de copyright
© 2021 Published by Elsevier Inc.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
RNA Biol. 2015;12(1):43-53
pubmed: 25625181
Curr Psychiatry Rep. 2012 Apr;14(2):129-37
pubmed: 22198824
Stem Cells. 2010 Jun;28(6):1060-70
pubmed: 20506192
Neural Plast. 2016;2016:8056370
pubmed: 26881133
Neurobiol Dis. 2018 Apr;112:1-13
pubmed: 29277556
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jan 10;104:110033
pubmed: 32640261
Trends Pharmacol Sci. 2016 Dec;37(12):1029-1044
pubmed: 27832923
J Affect Disord. 2019 Apr 1;248:81-90
pubmed: 30716615
J Cell Physiol. 2018 Jan;233(1):673-687
pubmed: 28332716
Development. 2017 Jul 1;144(13):2310-2322
pubmed: 28676566
Exp Neurol. 2016 Jul;281:99-108
pubmed: 27118371
PLoS One. 2012;7(10):e47073
pubmed: 23056585
J Neurosci. 2016 Aug 10;36(32):8441-52
pubmed: 27511015
J Neurochem. 2010 Jan;112(2):397-409
pubmed: 19878438
Biol Psychiatry. 2016 Dec 1;80(11):815-826
pubmed: 27016384
Philos Trans R Soc Lond B Biol Sci. 2012 Sep 5;367(1601):2475-84
pubmed: 22826346
PLoS One. 2012;7(5):e38174
pubmed: 22693596
Neurosci Lett. 2016 May 27;622:61-6
pubmed: 27102143
Pharmacol Biochem Behav. 2020 Jan;188:172837
pubmed: 31830487
Nucleic Acids Res. 2013 Jan 7;41(1):617-31
pubmed: 23166306
Am J Psychiatry. 2012 Nov;169(11):1150-6
pubmed: 23534055
Nature. 2008 Oct 16;455(7215):894-902
pubmed: 18923511
Neurotherapeutics. 2017 Jul;14(3):677-686
pubmed: 28397115
J Psychiatry Neurosci. 2009 Jan;34(1):41-54
pubmed: 19125212
Psychopharmacology (Berl). 2013 Jun;227(4):583-93
pubmed: 23377023
Neuropharmacology. 2018 Mar 15;131:364-376
pubmed: 29329879
Mol Neurobiol. 2016 Sep;53(7):4701-12
pubmed: 26319558
Neurobiol Stress. 2020 Jul 22;13:100243
pubmed: 33344699
Neuropsychopharmacology. 2013 Oct;38(11):2268-77
pubmed: 23680942
Brain Struct Funct. 2008 Sep;213(1-2):93-118
pubmed: 18704495
Neurochem Res. 2017 Mar;42(3):876-890
pubmed: 27882448
Sci Rep. 2016 May 25;6:26781
pubmed: 27221778
Mol Psychiatry. 2020 Mar;25(3):530-543
pubmed: 31801966
Mol Neurobiol. 2021 Apr;58(4):1330-1344
pubmed: 33165828
PLoS One. 2014 Nov 25;9(11):e113662
pubmed: 25423262
Nature. 2010 Aug 26;466(7310):1105-9
pubmed: 20622856
Mol Neurobiol. 2018 Oct;55(10):7717-7727
pubmed: 29460265
Neural Plast. 2016;2016:7267865
pubmed: 26966584
Front Cell Neurosci. 2020 Oct 28;14:573208
pubmed: 33192317
Mol Neurobiol. 2019 Dec;56(12):8617-8627
pubmed: 31292861
Nat Methods. 2012 Jun 28;9(7):676-82
pubmed: 22743772
Neuropsychopharmacology. 2014 Jan;39(1):233
pubmed: 24317309
Psychiatry Res Neuroimaging. 2020 Jul 30;301:111101
pubmed: 32447184
Mol Biol Cell. 2005 Dec;16(12):5630-8
pubmed: 16195345
Neuropsychopharmacology. 2016 Nov;41(12):2882-2892
pubmed: 27312407
Nature. 2006 Jan 19;439(7074):283-9
pubmed: 16421561
Eur J Hum Genet. 2014 Jun;22(6):840-3
pubmed: 24169524
J Exp Neurosci. 2016 Oct 05;10:101-120
pubmed: 27721656
Science. 2019 Apr 12;364(6436):
pubmed: 30975859
Exp Mol Med. 2018 Oct 29;50(10):1-14
pubmed: 30369596
Neurotox Res. 2020 Jan;37(1):171-182
pubmed: 31493120
Neurobiol Dis. 2012 May;46(2):272-8
pubmed: 22226785
Mol Psychiatry. 2017 Sep;22(9):1226-1227
pubmed: 27698433
J Neurosci. 2010 Jul 21;30(29):9695-707
pubmed: 20660252
Front Mol Neurosci. 2019 Oct 30;12:260
pubmed: 31736707
Nat Neurosci. 2012 Apr 08;15(5):697-699
pubmed: 22484572
Cereb Cortex. 2019 Jun 1;29(6):2737-2747
pubmed: 30843060
Neuropharmacology. 2016 Aug;107:305-316
pubmed: 27026110
Nucleic Acids Res. 2020 Jan 8;48(D1):D127-D131
pubmed: 31504780
Mol Neurobiol. 2016 Nov;53(9):6388-6396
pubmed: 26576957
Synapse. 2014 Sep;68(9):387-93
pubmed: 24753016
J Mol Neurosci. 2017 Feb;61(2):159-168
pubmed: 27924451
Prog Mol Biol Transl Sci. 2018;158:255-272
pubmed: 30072056
Neuropsychopharmacology. 2016 Jan;41(1):3-23
pubmed: 26076834
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jan 10;104:110053
pubmed: 32739332
Neuromolecular Med. 2014 Sep;16(3):594-605
pubmed: 24839168
Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8143-8153
pubmed: 32209671
Nat Rev Neurosci. 2011 Nov 30;13(1):22-37
pubmed: 22127301
Cell. 2005 Jan 14;120(1):15-20
pubmed: 15652477
Neuropsychopharmacology. 2008 Jan;33(1):88-109
pubmed: 17851537
Bioinformatics. 2012 Mar 15;28(6):771-6
pubmed: 22285563
Front Cell Neurosci. 2013 Nov 20;7:220
pubmed: 24312010
Elife. 2014 Nov 18;3:
pubmed: 25406064
Nat Neurosci. 2015 Oct;18(10):1353-63
pubmed: 26404710
Transl Psychiatry. 2019 Dec 9;9(1):333
pubmed: 31819045
Neurobiol Stress. 2019 Apr 02;10:100160
pubmed: 31193464
Nat Rev Neurosci. 2017 May 18;18(6):347-361
pubmed: 28515491
Brain Struct Funct. 2015 Jul;220(4):2387-99
pubmed: 24874920
Neuron. 2014 Feb 5;81(3):471-83
pubmed: 24507186
Neurobiol Learn Mem. 2015 Sep;123:225-38
pubmed: 26165635
Neuroscience. 2015 Apr 16;291:289-300
pubmed: 25665754
Psychiatry Res. 2012 Dec 30;200(2-3):1047-50
pubmed: 22796099
Int J Neuropsychopharmacol. 2013 Sep;16(8):1885-92
pubmed: 23684180
Int J Neuropsychopharmacol. 2015 Sep 07;19(3):pyv097
pubmed: 26346341
Front Neuroendocrinol. 2019 Apr;53:100744
pubmed: 31004616
Int J Clin Exp Pathol. 2019 Feb 01;12(2):628-639
pubmed: 31933869
Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4;64:341-8
pubmed: 25689819
Mol Psychiatry. 2018 Apr;23(4):812-823
pubmed: 29158584
Eur Neuropsychopharmacol. 2017 Oct;27(10):977-986
pubmed: 28870407
Oxid Med Cell Longev. 2018 Jan 31;2018:8596903
pubmed: 29643977
Neuron. 2019 Apr 3;102(1):75-90
pubmed: 30946828
Nat Commun. 2014;5:3263
pubmed: 24535612
Nature. 2015 Jul 30;523(7562):588-91
pubmed: 26176920
RNA Biol. 2017 Nov 2;14(11):1580-1591
pubmed: 28640668
Neuron. 2014 Jul 16;83(2):344-360
pubmed: 24952960
Biol Psychiatry. 2019 Mar 15;85(6):436-438
pubmed: 30777168
Neuropharmacology. 2012 Jan;62(1):63-77
pubmed: 21827775
J Biol Chem. 2020 Mar 6;295(10):3040-3054
pubmed: 32001620
Transl Psychiatry. 2020 Aug 3;10(1):264
pubmed: 32747631
Mol Ther Nucleic Acids. 2020 Sep 03;22:1063-1077
pubmed: 33294293
Mol Neurobiol. 2017 Jan;54(1):541-550
pubmed: 26742529
Circ Res. 2015 May 22;116(11):1753-64
pubmed: 25801897
Biol Psychiatry. 2011 Apr 15;69(8):754-61
pubmed: 21292242
Bipolar Disord. 2016 Dec;18(8):702-705
pubmed: 27900801
Psychiatr Danub. 2015 Sep;27 Suppl 1:S235-9
pubmed: 26417770
Int J Neuropsychopharmacol. 2014 May;17(5):779-91
pubmed: 24451568