Subacute Thyroiditis During the SARS-CoV-2 Pandemic.

SAT thyroid thyroid dysfunction thyroiditis viruses

Journal

Journal of the Endocrine Society
ISSN: 2472-1972
Titre abrégé: J Endocr Soc
Pays: United States
ID NLM: 101697997

Informations de publication

Date de publication:
01 Oct 2021
Historique:
received: 10 06 2021
entrez: 30 8 2021
pubmed: 31 8 2021
medline: 31 8 2021
Statut: epublish

Résumé

Acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been related to subacute thyroiditis (SAT). We compared SAT cases during the SARS-CoV-2 pandemic to those observed in the previous years. A cross-sectional, retrospective study was conducted at the Endocrinology Unit of University Hospital of Pisa, Italy. We included all patients observed from January 2016 to December 2020 because of an untreated SAT, who had developed the disease within 15 days prior to the visit. SAT cases from 2016 to 2019 (N = 152) are referred to as While during 2016-2019, most SAT cases were observed in the third quarter, in 2020, 2 peaks were seen, superimposable to the SARS-CoV-2 outbreaks in the second and the fourth quarters. In the second and fourth quarters of 2020, we observed higher levels of free thyroxine (FT4), C-reactive protein (CRP), and thyroglobulin (Tg) compared with the same quarters of the years 2016-2019. Pos-SARS-CoV-2 patients had higher FT4 (28.4 vs 24.1 nmol/L), CRP (8.5 vs 3.6 mg/L), and Tg (155 vs 60 µg/L) ( The SARS-CoV-2 pandemic has caused a shift in the annual timing and severity of SAT cases.

Identifiants

pubmed: 34458656
doi: 10.1210/jendso/bvab130
pii: bvab130
pmc: PMC8344892
doi:

Types de publication

Journal Article

Langues

eng

Pagination

bvab130

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the Endocrine Society.

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Auteurs

Alessandro Brancatella (A)

Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56127 Pisa, Italy.

Nicola Viola (N)

Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56127 Pisa, Italy.

Grazia Rutigliano (G)

Department of Pathology, University of Pisa, 56127 Pisa, Italy.

Daniele Sgrò (D)

Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56127 Pisa, Italy.

Ferruccio Santini (F)

Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56127 Pisa, Italy.

Francesco Latrofa (F)

Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56127 Pisa, Italy.

Classifications MeSH