Synthetic hyperacetylation of nucleosomal histones.
Journal
RSC chemical biology
ISSN: 2633-0679
Titre abrégé: RSC Chem Biol
Pays: England
ID NLM: 101768727
Informations de publication
Date de publication:
01 Jun 2020
01 Jun 2020
Historique:
received:
11
03
2020
accepted:
29
04
2020
entrez:
30
8
2021
pubmed:
19
5
2020
medline:
19
5
2020
Statut:
epublish
Résumé
We report combinations of a DMAP-based catalyst and phenyl acetate with optimal electron density as a new chemical system for high-yield, selective synthetic acetylation of histone lysine residues. The utility of this chemical system as a unique biologic tool is demonstrated by applying it to
Identifiants
pubmed: 34458748
doi: 10.1039/d0cb00029a
pii: d0cb00029a
pmc: PMC8341002
doi:
Types de publication
Journal Article
Langues
eng
Pagination
56-59Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
There are no conflicts to declare.
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