Care disruptions among patients with lung cancer: A COVID-19 and cancer outcomes study.


Journal

Lung cancer (Amsterdam, Netherlands)
ISSN: 1872-8332
Titre abrégé: Lung Cancer
Pays: Ireland
ID NLM: 8800805

Informations de publication

Date de publication:
10 2021
Historique:
received: 01 04 2021
revised: 07 06 2021
accepted: 09 07 2021
pubmed: 31 8 2021
medline: 24 9 2021
entrez: 30 8 2021
Statut: ppublish

Résumé

Patients with lung cancer (LC) are susceptible to severe outcomes from COVID-19. This study evaluated disruption to care of patients with LC during the COVID-19 pandemic. The COVID-19 and Cancer Outcomes Study (CCOS) is a prospective cohort study comprised of patients with a current or past history of hematological or solid malignancies with outpatient visits between March 2 and March 6, 2020, at two academic cancer centers in the Northeastern United States (US). Data was collected for the three months prior to the index week (baseline period) and the following three months (pandemic period). 313 of 2365 patients had LC, 1578 had other solid tumors, and 474 had hematological malignancies. Patients with LC were not at increased risk of COVID-19 diagnosis compared to patients with other solid or hematological malignancies. When comparing data from the pandemic period to the baseline period, patients with LC were more likely to have a decrease in in-person visits compared to patients with other solid tumors (aOR 1.94; 95% CI, 1.46-2.58), but without an increase in telehealth visits (aOR 1.13; 95% CI 0.85-1.50). Patients with LC were more likely to experience pandemic-related treatment delays than patients with other solid tumors (aOR 1.80; 95% CI 1.13-2.80) and were more likely to experience imaging/diagnostic procedure delays than patients with other solid tumors (aOR 2.59; 95% CI, 1.46-4.47) and hematological malignancies (aOR 2.01; 95% CI, 1.02-3.93). Among patients on systemic therapy, patients with LC were also at increased risk for decreased in-person visits and increased treatment delays compared to those with other solid tumors. Patients with LC experienced increased cancer care disruption compared to patients with other malignancies during the early phase of the COVID-19 pandemic. Focused efforts to ensure continuity of care for this patient population are warranted.

Identifiants

pubmed: 34461400
pii: S0169-5002(21)00455-4
doi: 10.1016/j.lungcan.2021.07.002
pmc: PMC8284065
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

78-83

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

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Auteurs

Sheena Bhalla (S)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Ziad Bakouny (Z)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Andrew L Schmidt (AL)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Chris Labaki (C)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

John A Steinharter (JA)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Douglas A Tremblay (DA)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Mark M Awad (MM)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Alaina J Kessler (AJ)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Robert I Haddad (RI)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Michelle Evans (M)

Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Fiona Busser (F)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Michael Wotman (M)

Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Catherine R Curran (CR)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Brittney S Zimmerman (BS)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Gabrielle Bouchard (G)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Tomi Jun (T)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Pier V Nuzzo (PV)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Qian Qin (Q)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Laure Hirsch (L)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Jonathan Feld (J)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Kaitlin M Kelleher (KM)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Danielle Seidman (D)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Hsin-Hui Huang (HH)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Heather M Anderson-Keightly (HM)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Talal El Zarif (T)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Sarah Abou Alaiwi (S)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Talia D Rosenbloom (TD)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Penina S Stewart (PS)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Matthew D Galsky (MD)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Toni K Choueiri (TK)

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Deborah B Doroshow (DB)

Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA. Electronic address: deborah.doroshow@mssm.edu.

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