Evidence of neutralizing antibodies against SARS-CoV-2 in domestic cats living with owners with a history of COVID-19 in Lima - Peru.

COVID-19 Cats Neutralizing antibodies One health SARS-CoV-2 Serology

Journal

One health (Amsterdam, Netherlands)
ISSN: 2352-7714
Titre abrégé: One Health
Pays: Netherlands
ID NLM: 101660501

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 26 05 2021
revised: 23 08 2021
accepted: 25 08 2021
pubmed: 1 9 2021
medline: 1 9 2021
entrez: 31 8 2021
Statut: ppublish

Résumé

SARS-CoV-2 can infect a variety of wild and domestic animals worldwide. Of these, domestic cats are highly susceptible species and potential viral reservoirs. As such, it is important to investigate disease exposure in domestic cats in areas with active community transmission and high disease prevalence. In this report we demonstrate the presence of serum neutralizing antibodies against the receptor binding-domain (RBD) of the SARS-CoV-2 in cats whose owners had been infected with SARS-CoV-2 in Lima, Peru, using a commercial competitive ELISA SARS-CoV-2 Surrogate Virus Neutralization Test. Out of 41 samples, 17.1% (7/41) and 31.7% (13/41) were positive, using the cut-off inhibition value of 30% and 20%, respectively. Not all cats living in a single house had detectable neutralizing antibodies showing heterogenous exposure and immunity among cohabiting animals. This is the first report of SARS-COV-2 exposure of domestic cats in Lima, Peru. Further studies are required to ascertain the prevalence of SARS-COV-2 exposure among domestic cats.

Identifiants

pubmed: 34462726
doi: 10.1016/j.onehlt.2021.100318
pii: S2352-7714(21)00108-7
pmc: PMC8388143
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100318

Subventions

Organisme : FIC NIH HHS
ID : D43 TW007393
Pays : United States

Commentaires et corrections

Type : UpdateOf

Informations de copyright

© 2021 The Authors. Published by Elsevier B.V.

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Auteurs

Luis M Jara (LM)

Facultad de Medicina Veterinaria y Zootecnia, Universidad Peruana Cayetano Heredia, Lima, Peru.

Cusi Ferradas (C)

Unidad de Investigación en Enfermedades Emergentes y Cambio Climático (Emerge), Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Peru.

Francesca Schiaffino (F)

Facultad de Medicina Veterinaria y Zootecnia, Universidad Peruana Cayetano Heredia, Lima, Peru.

Camila Sánchez-Carrión (C)

Clínica Veterinaria Gatuario, Lima, Peru.

Ana Martínez-Vela (A)

Clínica Veterinaria Los Dominicos, Lima, Peru.

Alexandra Ulloa (A)

Clínica Veterinaria Gatuario, Lima, Peru.

Gisela Isasi-Rivas (G)

Farmacológicos Veterinarios (FARVET), Chincha, Peru.

Angela Montalván (A)

Farmacológicos Veterinarios (FARVET), Chincha, Peru.

Luis Guevara Sarmiento (LG)

Farmacológicos Veterinarios (FARVET), Chincha, Peru.

Manolo Fernández (M)

Farmacológicos Veterinarios (FARVET), Chincha, Peru.

Mirko Zimic (M)

Farmacológicos Veterinarios (FARVET), Chincha, Peru.
Laboratorio de Bioinformática, Biología Molecular y Desarrollos Tecnológicos, Universidad Peruana Cayetano Heredia, Lima, Peru.

Classifications MeSH