An Essential Role of UBXN3B in B Lymphopoiesis.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
24 Aug 2021
24 Aug 2021
Historique:
entrez:
31
8
2021
pubmed:
1
9
2021
medline:
1
9
2021
Statut:
epublish
Résumé
Hematopoiesis is finely regulated to enable timely production of the right numbers and types of mature immune cells to maintain tissue homeostasis. Dysregulated hematopoiesis may compromise antiviral immunity and/or exacerbate immunopathogenesis. Herein, we report an essential role of UBXN3B in maintenance of hematopoietic homeostasis and restriction of immunopathogenesis during respiratory viral infection.
Identifiants
pubmed: 34462748
doi: 10.1101/2021.03.04.433919
pmc: PMC8404893
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : NIAID NIH HHS
ID : R01 AI127865
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI132526
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI155820
Pays : United States