Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression.
Caveolin-1
Glycosylation
N-glycan
Sialyltransferase
Journal
Journal of physiology and biochemistry
ISSN: 1877-8755
Titre abrégé: J Physiol Biochem
Pays: Spain
ID NLM: 9812509
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
28
06
2020
accepted:
19
08
2021
pubmed:
1
9
2021
medline:
1
3
2022
entrez:
31
8
2021
Statut:
ppublish
Résumé
Caveolin-1 (Cav-1) is a constitutive protein within caveolar membranes. Previous studies from our group and others indicated that Cav-1 could mediate N-glycosylation, α2,6-sialylation, and fucosylation in mouse hepatocarcinoma cells in vitro. However, little is known about the effect of Cav-1 expression on glycosylation modifications in vivo. In this study, the N-glycan profiles in serum from Cav-1
Identifiants
pubmed: 34462883
doi: 10.1007/s13105-021-00840-x
pii: 10.1007/s13105-021-00840-x
doi:
Substances chimiques
Caveolin 1
0
Polysaccharides
0
Sialyltransferases
EC 2.4.99.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
73-83Subventions
Organisme : the Major State Basic Research Development Program of China
ID : NO. 2012CB822103
Organisme : the National Natural Science Foundation of China
ID : NO. 31570802
Informations de copyright
© 2021. University of Navarra.
Références
Arpaia E, Blaser H, Quintela-Fandino M, Duncan G, Leong HS, Ablack A, Nambiar SC, Lind EF, Silvester J, Fleming CK, Rufini A, Tusche MW, Brustle A, Ohashi PS, Lewis JD, Mak TW (2012) The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk. Oncogene 31:884–896. https://doi.org/10.1038/onc.2011.288
doi: 10.1038/onc.2011.288
pubmed: 21765460
Bull C, Stoel MA, den Brok MH, Adema GJ (2014) Sialic acids sweeten a tumor’s life. Cancer Res 74:3199–3204. https://doi.org/10.1158/0008-5472.CAN-14-0728
doi: 10.1158/0008-5472.CAN-14-0728
pubmed: 24830719
Cheng JPX, Nichols BJ (2016) Caveolae: one function or many? Trends Cell Biol 26:177–189. https://doi.org/10.1016/j.tcb.2015.10.010
doi: 10.1016/j.tcb.2015.10.010
pubmed: 26653791
Clerc F, Novokmet M, Dotz V, Reiding KR, de Haan N, Kammeijer GSM, Dalebout H, Bladergroen MR, Vukovic F, Rapp E, Targan SR, Barron G, Manetti N, Latiano A, McGovern DPB, Annese V, Lauc G, Wuhrer M, Consortium I-B (2018) Plasma N-glycan signatures are associated with features of inflammatory bowel diseases. Gastroenterology 155:829–843. https://doi.org/10.1053/j.gastro.2018.05.030
doi: 10.1053/j.gastro.2018.05.030
pubmed: 29792883
Codrici E, Albulescu L, Popescu ID, Mihai S, Enciu AM, Albulescu R, Tanase C, Hinescu ME (2018) Caveolin-1-knockout mouse as a model of inflammatory diseases. J Immunol Res 2018:2498576. https://doi.org/10.1155/2018/2498576
Dalziel M, Dall’Olio F, Mungul A, Piller V, Piller F (2004) Ras oncogene induces beta-galactoside alpha2,6-sialyltransferase (ST6Gal I) via a RalGEF-mediated signal to its housekeeping promoter. Eur J Biochem 271:3623–3634. https://doi.org/10.1111/j.1432-1033.2004.04284.x
doi: 10.1111/j.1432-1033.2004.04284.x
pubmed: 15355339
Deng SK, Xiang YL, Yi LI, Hou XY, Shen L (2017) Alterations of caveolin-1 and adhesion molecules in a mouse model of acute lung injury induced by lipopolysaccharide. Life Sci Res 21:325–328. https://doi.org/10.16605/j.cnki.1007-7847.2017.04.008
Domino SE, Hiraiwa N, Lowe JB (1997) Molecular cloning, chromosomal assignment and tissue-specific expression of a murine alpha(1,2)fucosyltransferase expressed in thymic and epididymal epithelial cells. Biochem J 327(Pt 1):105–115. https://doi.org/10.1042/bj3270105
doi: 10.1042/bj3270105
pubmed: 9355741
pmcid: 1218769
Dotz V, Lemmers RFH, Reiding KR, HipgraveEderveen AL, Lieverse AG, Mulder MT, Sijbrands EJG, Wuhrer M, van Hoek M (2018) Plasma protein N-glycan signatures of type 2 diabetes. Biochim Biophys Acta 1862:2613–2622. https://doi.org/10.1016/j.bbagen.2018.08.005
doi: 10.1016/j.bbagen.2018.08.005
Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV (2001) Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293:2449–2452. https://doi.org/10.1126/science.1062688
doi: 10.1126/science.1062688
pubmed: 11498544
Gersten KM, Natsuka S, Trinchera M, Petryniak B, Kelly RJ, Hiraiwa N, Jenkins NA, Gilbert DJ, Copeland NG, Lowe JB (1995) Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase. J Biol Chem 270:25047–25056. https://doi.org/10.1074/jbc.270.42.25047
doi: 10.1074/jbc.270.42.25047
pubmed: 7559635
Huang CC, Liu YM, Wu HM, Sun DH, Li Y (2017) Characterization of IgG glycosylation in rheumatoid arthritis patients by MALDI-TOF-MSn and capillary electrophoresis. Anal Bioanal Chem 409:3731–3739. https://doi.org/10.1007/s00216-017-0302-1
doi: 10.1007/s00216-017-0302-1
pubmed: 28397166
Jian Q, Yang Z, Shu J, Liu XW, Zhang J, Li Z (2018) Lectin BS-I inhibits cell migration and invasion via AKT/GSK-3 beta/beta-catenin pathway in hepatocellular carcinoma. J Cell Mol Med 22:315–329. https://doi.org/10.1111/jcmm.13320
doi: 10.1111/jcmm.13320
pubmed: 28922551
Lee SJ, Evers S, Roeder D, Parlow AF, Risteli J, Risteli L, Lee YC, Feizi T, Langen H, Nussenzweig MC (2002) Mannose receptor-mediated regulation of serum glycoprotein homeostasis. Science 295:1898–1901. https://doi.org/10.1126/science.1069540
doi: 10.1126/science.1069540
pubmed: 11884756
Lim JS, Nguyen KC, Han JM, Jang IS, Fabian C, Cho KA (2015) Direct regulation of TLR5 Expression by caveolin-1. Mol Cells 38:1111–1117. https://doi.org/10.14348/molcells.2015.0213
Lim JS, Nguyen KCT, Nguyen CT, Jang IS, Han JM, Fabian C, Lee SE, Rhee JH, Cho KA (2015) Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence. Aging Cell 14:907–915. https://doi.org/10.1111/acel.12383
doi: 10.1111/acel.12383
pubmed: 26223660
pmcid: 4568978
Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, Sessa WC (2007) Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. J Exp Med 204:2373–2382. https://doi.org/10.1084/jem.20062340
doi: 10.1084/jem.20062340
pubmed: 17893196
pmcid: 2118452
Ohtsubo K, Marth JD (2006) Glycosylation in cellular mechanisms of health and disease. Cell 126:855–867. https://doi.org/10.1016/j.cell.2006.08.019
doi: 10.1016/j.cell.2006.08.019
pubmed: 16959566
Park DS, Cohen AW, Frank PG, Razani B, Lee HK, Williams TM, Chandra M, Shirani J, De Souza AP, Tang BY, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP (2003) Caveolin-1 null (-/-) mice show dramatic reductions in life span. Biochemistry-Us 42:15124–15131. https://doi.org/10.1021/Bi0356348
doi: 10.1021/Bi0356348
Parton RG (2018) Caveolae: structure, function, and relationship to disease. Annu Rev Cell Dev Bi 34:111–136. https://doi.org/10.1146/annurev-cellbio-100617-062737
doi: 10.1146/annurev-cellbio-100617-062737
Quest AFG, Gutierrez-Pajares JL, Torres VA (2008) Caveolin-1: an ambiguous partner in cell signalling and cancer. J Cell Mol Med 12:1130–1150. https://doi.org/10.1111/j.1582-4934.2008.00331.x
doi: 10.1111/j.1582-4934.2008.00331.x
pubmed: 18400052
pmcid: 3865655
Raju TS, Briggs JB, Chamow SM, Winkler ME, Jones AJS (2001) Glycoengineering of therapeutic glycoproteins: in vitro galactosylation and sialylation of glycoproteins with terminal N-acetylglucosamine and galactose residues. Biochemistry-Us 40:8868–8876. https://doi.org/10.1021/bi010475i
doi: 10.1021/bi010475i
Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li MM, Pestell RG, Di Vizio D, Hou H, Kneitz B, Lagaud G, Christ GJ, Edelmann W, Lisanti MP (2001) Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem 276:38121–38138. https://doi.org/10.1074/jbc.M105408200
doi: 10.1074/jbc.M105408200
pubmed: 11457855
Reily C, Stewart TJ, Renfrow MB, Novak J (2019) Glycosylation in health and disease. Nat Rev Nephrol 15:346–366. https://doi.org/10.1038/s41581-019-0129-4
doi: 10.1038/s41581-019-0129-4
pubmed: 30858582
pmcid: 6590709
Sasai K, Ikeda Y, Ihara H, Honke K, Taniguchi N (2003) Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase III within the golgi apparatus. J Biol Chem 278:25295–25301. https://doi.org/10.1074/jbc.M301913200
doi: 10.1074/jbc.M301913200
pubmed: 12716887
Turner GA (1992) N-glycosylation of serum-proteins in disease and its investigation using lectins. Clin Chim Acta 208:149–171. https://doi.org/10.1016/0009-8981(92)90073-Y
doi: 10.1016/0009-8981(92)90073-Y
pubmed: 1499135
Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH (2015) Essentials of glycobiology, 3rd edn. Cold Spring Harbor. New York
Walz G, Aruffo A, Kolanus W, Bevilacqua M, Seed B (1990) Recognition by Elam-1 of the Sialyl-Lex determinant on myeloid and tumor-cells. Science 250:1132–1135. https://doi.org/10.1126/science.1701275
doi: 10.1126/science.1701275
pubmed: 1701275
Wang XN, Deng Z, Huang CC, Zhu T, Lou JT, Wang L, Li Y (2018) Differential N-glycan patterns identified in lung adenocarcinoma by N-glycan profiling of formalin-fixed paraffin-embedded (FFPE) tissue sections. J Proteomics 172:1–10. https://doi.org/10.1016/j.jprot.2017.11.010
doi: 10.1016/j.jprot.2017.11.010
pubmed: 29157724
Yu HJ, Li XJ, Chen MT, Zhang F, Liu XW, Yu JM, Zhong YG, Shu J, Chen WT, Du HQ, Zhang K, Zhang C, Zhang J, Xie H, Li Z (2019) Integrated glycome strategy for characterization of aberrant LacNAc contained N-glycans associated with gastric carcinoma. Front Oncol 9:636. https://doi.org/10.3389/fonc.2019.00636
doi: 10.3389/fonc.2019.00636
pubmed: 31355147
pmcid: 6636412
Yu HJ, Shu J, Li Z (2020) Lectin microarrays for glycoproteomics: an overview of their use and potential. Expert Rev Proteomic 17:27–39. https://doi.org/10.1080/14789450.2020.1720512
doi: 10.1080/14789450.2020.1720512
Yu S, Fan J, Liu L, Zhang L, Wang S, Zhang J (2013) Caveolin-1 up-regulates integrin alpha2,6-sialylation to promote integrin alpha5beta1-dependent hepatocarcinoma cell adhesion. FEBS Lett 587:782–787. https://doi.org/10.1016/j.febslet.2013.02.002
doi: 10.1016/j.febslet.2013.02.002
pubmed: 23416306
Yu S, Zhang L, Li N, Fan J, Liu L, Zhang J, Wang S (2012) Caveolin-1 up-regulates ST6Gal-I to promote the adhesive capability of mouse hepatocarcinoma cells to fibronectin via FAK-mediated adhesion signaling. Biochem Biophys Res Commun 427:506–512. https://doi.org/10.1016/j.bbrc.2012.09.086
doi: 10.1016/j.bbrc.2012.09.086
pubmed: 23022190
Yuan Q, Chen X, Han Y, Lei T, Wu Q, Yu X, Wang L, Fan Z, Wang S (2018) Modification of alpha2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway. Int J Cancer 143:2319–2330. https://doi.org/10.1002/ijc.31737
doi: 10.1002/ijc.31737
pubmed: 29981167
Zhang C, Huang H, Zhang JS, Wu Q, Chen XX, Huang TM, Li WL, Liu YB, Zhang JN (2019) Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma. Cell Death Dis 10:477. https://doi.org/10.1038/S41419-019-1703-1
doi: 10.1038/S41419-019-1703-1
pubmed: 31209283
pmcid: 6572835
Zhang C, Wu Q, Huang H, Chen XX, Huang TM, Li WL, Zhang JN, Liu YB (2020) Caveolin-1 upregulates Fut8 expression by activating the Wnt/beta-catenin pathway to enhance HCC cell proliferative and invasive ability. Cell Biol Int. https://doi.org/10.1002/cbin.11426
doi: 10.1002/cbin.11426
pubmed: 33325083
pmcid: 7894547
Zhong YG, Guo YH, Liu XW, Zhang JX, Ma TR, Shu J, Yang JJ, Zhang J, Jia ZS, Li Z (2017) Serum glycopatterns as novel potential biomarkers for diagnosis of acute-on-chronic hepatitis B liver failure. Sci Rep-Uk 7:45957. https://doi.org/10.1038/Srep45957
doi: 10.1038/Srep45957