Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohistochemical study of 10 cases.

PLEVA SARS-CoV-2 dermatopathology pediatric skin histopathology

Journal

Pediatric dermatology
ISSN: 1525-1470
Titre abrégé: Pediatr Dermatol
Pays: United States
ID NLM: 8406799

Informations de publication

Date de publication:
Sep 2021
Historique:
pubmed: 1 9 2021
medline: 11 11 2021
entrez: 31 8 2021
Statut: ppublish

Résumé

We observed ten children with a papular eruption with purpuric features during the SARS-CoV-2 pandemic in Northern Italy (May-December 2020). Histological examination showed signs of SARS-CoV-2-related dermatosis. Evidence of nucleocapsid viral proteins using SARS-CoV-2 (2019-nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.

Identifiants

pubmed: 34463363
doi: 10.1111/pde.14777
pmc: PMC8646411
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1185-1190

Informations de copyright

© 2021 Wiley Periodicals LLC.

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Auteurs

Raffaele Gianotti (R)

Department of Pathophysiology and Transplantation, Dermatology Unit, Università degli Studi di Milano, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Lucia Restano (L)

Department of Clinical Sciences and Community Health, Pediatric Dermatology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Mario Cutrone (M)

Dipartimento Materno Infantile Unità Operativa di Pediatria e Patologia Neonatale, Vicenza, Italy.

Cristiana Colonna (C)

Department of Clinical Sciences and Community Health, Pediatric Dermatology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Giovanni Fellegara (G)

Pathology Unit C.D.I. Centro Diagnostico Italiano S.p.A. Milan, Milan, Italy.

Isacco Debernardi (I)

Pathology Unit C.D.I. Centro Diagnostico Italiano S.p.A. Milan, Milan, Italy.

Francesca Boggio (F)

Division of Pathology, Università degli Studi di Milano, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Alessandro Del Gobbo (A)

Division of Pathology, Università degli Studi di Milano, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Nicola Adriano Monzani (NA)

Department of Clinical Sciences and Community Health, Neonatal Intensive Care Unit, IRCCS Foundation Cà Granda, Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.

Claudio Tripodo (C)

Tumor Immunology Unit. Department of Health Sciences, Istituto di Patologia Generale, University of Palermo School of Medicine, Palermo, Italy.

Carlo Gelmetti (C)

Department of Clinical Sciences and Community Health, Pediatric Dermatology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Emilio Berti (E)

Department of Pathophysiology and Transplantation, Dermatology Unit, Università degli Studi di Milano, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

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Classifications MeSH