Identification of Aptamers that Specifically Bind to A
ABO Blood-Group System
Antibodies
Flow Cytometry
SELEX Aptamer Technique
Journal
Galen medical journal
ISSN: 2322-2379
Titre abrégé: Galen Med J
Pays: Iran
ID NLM: 101625418
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
07
2019
revised:
12
08
2019
accepted:
10
11
2019
entrez:
1
9
2021
pubmed:
27
6
2020
medline:
27
6
2020
Statut:
epublish
Résumé
The apply of aptamers as a new generation's way to probe diagnostic for the detection of target molecules has gained ground. Aptamers can be used as alternatives to diagnostic antibodies for detection of blood groups due to their unique features. This study was aimed to produce DNA diagnostic aptamer detecting the antigen of A DNA aptamer was isolated against A The aptameric sequence obtained from C The aptamer obtained from using Cell-Selex method could be used as an example for the development of diagnostic tools such as biosensors for detecting A
Sections du résumé
BACKGROUND
BACKGROUND
The apply of aptamers as a new generation's way to probe diagnostic for the detection of target molecules has gained ground. Aptamers can be used as alternatives to diagnostic antibodies for detection of blood groups due to their unique features. This study was aimed to produce DNA diagnostic aptamer detecting the antigen of A
MATERIALS AND METHODS
METHODS
DNA aptamer was isolated against A
RESULTS
RESULTS
The aptameric sequence obtained from C
CONCLUSION
CONCLUSIONS
The aptamer obtained from using Cell-Selex method could be used as an example for the development of diagnostic tools such as biosensors for detecting A
Identifiants
pubmed: 34466563
doi: 10.31661/gmj.v9i0.1657
pmc: PMC8343710
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e1657Informations de copyright
Copyright© 2020, Galen Medical Journal.
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