Impact of preemptive hospitalization on health outcomes at the temporary COVID-19 hospital in Mexico City: a prospective observational study.

In response to the evolution of the coronavirus disease 2019 (COVID-19) pandemic, the admission protocol for the temporary COVID-19 hospital in Mexico City has been updated to hospitalize patients preemptively with an oxygen saturation (SpO This prospective, observational, single-center study compared the progression and outcomes of patients who were preemptively hospitalized Preemptive hospitalization significantly reduced the requirement for oxygen therapy (odds ratio 0.45, 95% confidence interval 0.31-0.66), admission to the intensive care unit (ICU) (0.37, 0.23-0.60), requirement for invasive mechanical ventilation (IMV) (0.40, 0.25-0.64), and mortality (0.22, 0.10-0.50). Stratification by CALL score at admission showed that the benefit of preemptive hospitalization remained significant for patients requiring oxygen therapy (0.51, 0.31-0.83), admission to the ICU (0.48, 0.27-0.86), and IMV (0.51, 0.28-0.92). Mortality risk remained significantly reduced (0.19, 0.07-0.48). Preemptive hospitalization reduced the rate of disease progression and may be beneficial for improving COVID-19 patient outcomes.

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© The Author(s), 2021.

Déclaration de conflit d'intérêts

Conflict of interest statement: The Carlos Slim Foundation funded this study. The funding source was involved in the design of the study, analysis, interpretation of data, and in writing the manuscript. The authors HGR, JLG, RSM, LAMJ, and RTC are employees of the Carlos Slim Foundation in Mexico. RRVV, RVB, LMJ, MAA, STB, RVAW, ESL, MDNO, AGR, LMBR, PEC, LERG, ACS, JBM, AGR, APC, HHB, LVA, and RARL are employed full-time by the temporary COVID-19 hospital. The authors declare no other outside funding from any other organizations and declare no further conflicts.