Cytologic features of oral squamous cell carcinoma in an Indo-Pacific bottlenose dolphin (Tursiops aduncus): Papanicolaou stain and immunocytochemistry using liquid-based cytology.
Papanicolaou stain
SCC
SurePath method
immunocytochemistry
liquid-based cytology
oral squamous cell carcinoma
p53
Journal
Veterinary clinical pathology
ISSN: 1939-165X
Titre abrégé: Vet Clin Pathol
Pays: United States
ID NLM: 9880575
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
revised:
04
01
2021
received:
14
09
2020
accepted:
04
01
2021
pubmed:
3
9
2021
medline:
1
10
2021
entrez:
2
9
2021
Statut:
ppublish
Résumé
Although oral cytology using Papanicolaou stain is useful for the early detection of oral premalignant lesions and squamous cell carcinoma (SCC) in people, little work has been conducted on this topic in veterinary medicine. This paper describes the features of oral cytology using Papanicolaou stain and immunocytochemistry on liquid-based cytology slides in a case of oral SCC in an Indo-Pacific bottlenose dolphin (Tursiops aduncus). In this case, dysplastic cells with koilocyte-like changes and SCC cells were identified using the Papanicolaou stain. These cells were positive for p53 using an immunocytochemistry analysis. A cytologic diagnosis of SCC was made. We believe that the early detection of premalignant oral lesions and SCC in dolphins can be significantly improved with cytology using liquid-based cytology, Papanicolaou staining, and immunocytochemistry.
Substances chimiques
Coloring Agents
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
404-409Subventions
Organisme : JSPS KAKENHI
ID : 20K20664
Informations de copyright
© 2021 American Society for Veterinary Clinical Pathology.
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