Concomitant falciparum malaria and Hyperreactive Malarial Splenomegaly in an adolescent boy from eastern India: A tale of rare coincidences.


Journal

Journal of vector borne diseases
ISSN: 0972-9062
Titre abrégé: J Vector Borne Dis
Pays: India
ID NLM: 101212761

Informations de publication

Date de publication:
Historique:
entrez: 2 9 2021
pubmed: 1 7 2020
medline: 15 12 2021
Statut: ppublish

Résumé

Hyperreactive malarial splenomegaly (HMS) is one of the important causes of massive splenomegaly in malaria endemic zones. It is thought to represent a dysfunctional immune response to recurrent malarial infection. It is usually reported due to physical symptoms of splenomegaly and hypersplenism and fever is classically absent. Concomitant malaria with HMS is a very rare finding in the Indian context. Here, we report a case of symptomatic falciparum malaria presented with fever, jaundice, massive splenomegaly and pancytopenia. Persistent massive splenomegaly led us to investigate thoroughly and finally diagnosed it as HMS with concomitant falciparum malaria. He received standard antimalarial treatment and 12 months of weekly chloroquine and completely recovered without any relapse or complications.

Identifiants

pubmed: 34472512
pii: JVectorBorneDis_2020_57_3_274_311782
doi: 10.4103/0972-9062.311782
doi:

Substances chimiques

Antimalarials 0
Chloroquine 886U3H6UFF

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

274-276

Déclaration de conflit d'intérêts

None

Auteurs

Saurabh Pandey (S)

Department of Internal Medicine, King George Medical University, Shamina road, Lucknow-226001, Uttar Pradesh, India.

Prantiki Halder (P)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Arnab Patra (A)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Mausam Mondal (M)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Subir Ghosh (S)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Dipankar Pal (D)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Soumen Nath Halder (SN)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Dolon Champa Modak (DC)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

Subhashish Kamal Guha (SK)

Department of Tropical Medicine, School of Tropical Medicine, 108 C R Avenue, Kolkata-700073, West Bengal, India.

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Classifications MeSH