Concomitant falciparum malaria and Hyperreactive Malarial Splenomegaly in an adolescent boy from eastern India: A tale of rare coincidences.
Hyperreactive malarial splenomegaly; concomitant malaria; Fakunle criteria
India
Journal
Journal of vector borne diseases
ISSN: 0972-9062
Titre abrégé: J Vector Borne Dis
Pays: India
ID NLM: 101212761
Informations de publication
Date de publication:
Historique:
entrez:
2
9
2021
pubmed:
1
7
2020
medline:
15
12
2021
Statut:
ppublish
Résumé
Hyperreactive malarial splenomegaly (HMS) is one of the important causes of massive splenomegaly in malaria endemic zones. It is thought to represent a dysfunctional immune response to recurrent malarial infection. It is usually reported due to physical symptoms of splenomegaly and hypersplenism and fever is classically absent. Concomitant malaria with HMS is a very rare finding in the Indian context. Here, we report a case of symptomatic falciparum malaria presented with fever, jaundice, massive splenomegaly and pancytopenia. Persistent massive splenomegaly led us to investigate thoroughly and finally diagnosed it as HMS with concomitant falciparum malaria. He received standard antimalarial treatment and 12 months of weekly chloroquine and completely recovered without any relapse or complications.
Identifiants
pubmed: 34472512
pii: JVectorBorneDis_2020_57_3_274_311782
doi: 10.4103/0972-9062.311782
doi:
Substances chimiques
Antimalarials
0
Chloroquine
886U3H6UFF
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
274-276Déclaration de conflit d'intérêts
None