Climate change and nephrology.

CKD of non-traditional cause CKD of uncertain etiology CKD of unknown etiology Mesoamerican nephropathy Sri Lankan nephropathy dehydration global warming heat stress heat stroke nephrolithiasis

Journal

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
ISSN: 1460-2385
Titre abrégé: Nephrol Dial Transplant
Pays: England
ID NLM: 8706402

Informations de publication

Date de publication:
23 Jan 2023
Historique:
received: 07 06 2021
pubmed: 3 9 2021
medline: 26 1 2023
entrez: 2 9 2021
Statut: ppublish

Résumé

Climate change should be of special concern for the nephrologist, as the kidney has a critical role in protecting the host from dehydration, but it is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney. The most severe presentation of heat stress is heat stroke, which can result in severe electrolyte disturbance and both acute and chronic kidney disease (CKD). However, lesser levels of heat stress also have multiple effects, including exacerbating kidney disease and precipitating cardiovascular events in subjects with established kidney disease. Heat stress can also increase the risk for kidney stones, cause multiple electrolyte abnormalities and induce both acute and chronic kidney disease. Recently there have been multiple epidemics of CKD of uncertain etiology in various regions of the world, including Mesoamerica, Sri Lanka, India and Thailand. There is increasing evidence that climate change and heat stress may play a contributory role in these conditions, although other causes, including toxins, could also be involved. As climate change worsens, the nephrologist should prepare for an increase in diseases associated with heat stress and dehydration.

Identifiants

pubmed: 34473287
pii: 6362903
doi: 10.1093/ndt/gfab258
pmc: PMC9869860
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

41-48

Subventions

Organisme : NIH HHS
ID : DK125351
Pays : United States
Organisme : La Isla Network

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of ERA. All rights reserved.

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Auteurs

Fumihiko Sasai (F)

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Carlos Roncal-Jimenez (C)

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Keegan Rogers (K)

Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Yuka Sato (Y)

Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Jared M Brown (JM)

Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Jason Glaser (J)

La Isla Network, Léon, Nicaragua.

Gabriela Garcia (G)

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Laura Gabriela Sanchez-Lozada (LG)

Laboratory of Renal Physiopathology, Instituto Nacional de Cardiologia, Ignacio Chavez, Mexico City.

Bernardo Rodriguez-Iturbe (B)

Laboratory of Renal Physiopathology, Instituto Nacional de Cardiologia, Ignacio Chavez, Mexico City.
Instituto Nacional de Cencias Médicas y Nutrición "Salvador Zubirán", Department of Nephrology, Mexico City, Mexico.

Jaime Butler Dawson (JB)

Center for Health, Work and Environment, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Cecilia Sorensen (C)

Center for Health, Work and Environment, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Ana Andres Hernando (AA)

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Marvin Gonzalez-Quiroz (M)

Research Centre on Health, Work and Environment (CISTA), National Autonomous University of Nicaragua, León, Nicaragua.
Centre for Nephrology, University College London, London, UK.

Miguel Lanaspa (M)

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Lee S Newman (LS)

Center for Health, Work and Environment, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Richard J Johnson (RJ)

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

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Classifications MeSH