A Strategy to Conjugate Bioactive Fragments to Cytotoxic Diiron Bis(cyclopentadienyl) Complexes.
Journal
Organometallics
ISSN: 0276-7333
Titre abrégé: Organometallics
Pays: United States
ID NLM: 9881295
Informations de publication
Date de publication:
09 Aug 2021
09 Aug 2021
Historique:
received:
03
05
2021
entrez:
3
9
2021
pubmed:
4
9
2021
medline:
4
9
2021
Statut:
ppublish
Résumé
A series of bioactive molecules were synthesized from the condensation of aspirin or chlorambucil with terminal alkynes bearing alcohol or amine substituents. Insertion of the resulting alkynes into the iron-carbyne bond of readily accessible diiron bis(cyclopentadienyl) μ-aminocarbyne complexes, [
Identifiants
pubmed: 34475610
doi: 10.1021/acs.organomet.1c00270
pmc: PMC8397425
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2516-2528Informations de copyright
© 2021 The Authors. Published by American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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