[Experience with endoscopic submucosal dissection for the treatment of early neoplasms of the digestive tract].

Disección endoscópica submucosa para el tratamiento de neoplasias incipientes del tubo digestivo: experiencia en un centro universitario de alto volumen.

Journal

Revista medica de Chile
ISSN: 0717-6163
Titre abrégé: Rev Med Chil
Pays: Chile
ID NLM: 0404312

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 15 07 2020
accepted: 27 01 2021
entrez: 3 9 2021
pubmed: 4 9 2021
medline: 8 9 2021
Statut: ppublish

Résumé

Endoscopic submucosal dissection (ESD) allows en-bloc resection of early gastro-intestinal neoplasms (EGIN) with healing potential. To describe the results of patients treated with ESD for EGIN by our team. Descriptive study of patients with EGIN who underwent ESD with curative intention between January 2008 and March 2020. One hundred thirty-two ESD were performed in 127 patients. 77% were gastric lesions, 14% colorectal, 8% esophageal and 1% duodenal. En-bloc resection was achieved in 98.4% of ESDs. Eighty eight percent of patients met curative standards. Overall, cancer-specific, and recurrence-free survival were 95%, 100% and 98% respectively. ESD allows en-bloc resections with curative potential in selected patients, but with a significant reduction in morbidity and mortality and less impact on quality of life. Our results suggest the feasibility to perform ESD in our country with results comparable to those reported in the literature.

Sections du résumé

BACKGROUND BACKGROUND
Endoscopic submucosal dissection (ESD) allows en-bloc resection of early gastro-intestinal neoplasms (EGIN) with healing potential.
AIM OBJECTIVE
To describe the results of patients treated with ESD for EGIN by our team.
PATIENTS AND METHODS METHODS
Descriptive study of patients with EGIN who underwent ESD with curative intention between January 2008 and March 2020.
RESULTS RESULTS
One hundred thirty-two ESD were performed in 127 patients. 77% were gastric lesions, 14% colorectal, 8% esophageal and 1% duodenal. En-bloc resection was achieved in 98.4% of ESDs. Eighty eight percent of patients met curative standards. Overall, cancer-specific, and recurrence-free survival were 95%, 100% and 98% respectively.
CONCLUSIONS CONCLUSIONS
ESD allows en-bloc resections with curative potential in selected patients, but with a significant reduction in morbidity and mortality and less impact on quality of life. Our results suggest the feasibility to perform ESD in our country with results comparable to those reported in the literature.

Identifiants

pubmed: 34479336
pii: S0034-98872021000400501
doi: 10.4067/s0034-98872021000400501
pii:
doi:

Types de publication

Journal Article

Langues

spa

Sous-ensembles de citation

IM

Pagination

501-507

Auteurs

Ricardo Mejía (R)

División de Cirugía, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Josefina Sáez (J)

Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Pamela Briones (P)

Unidad Docente Asociada, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile.

Enrique Norero (E)

Unidad Docente Asociada, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile.

Marco Ceroni (M)

Unidad Docente Asociada, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile.

Alfonso Díaz (A)

Unidad Docente Asociada, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile.

Allan Sharp (A)

División de Cirugía, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

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Classifications MeSH