Haematological malignancies in sub-Saharan Africa: east Africa as an example for improving care.


Journal

The Lancet. Haematology
ISSN: 2352-3026
Titre abrégé: Lancet Haematol
Pays: England
ID NLM: 101643584

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 12 09 2020
revised: 15 06 2021
accepted: 25 06 2021
pubmed: 6 9 2021
medline: 30 9 2021
entrez: 5 9 2021
Statut: ppublish

Résumé

Haematological malignancies account for almost 10% of all cancers diagnosed in sub-Saharan Africa, although the exact incidences and treatment outcomes are difficult to discern because population-based cancer registries in the region are still underdeveloped. More research on haematological malignancies in sub-Saharan Africa is required to establish whether these cancers have a natural history similar to those diagnosed in high-income countries, about which more is known. Several factors negatively affect the outcome of haematological malignancies in sub-Saharan Africa, showcasing a need for improved understanding of the clinicobiological profile of these cancers to facilitate prevention, early detection, diagnosis, and appropriate treatment through increased capacity building, infrastructure, community awareness, coordinated resource mobilisation, and collaboration across the world. The east African governments have pooled resources for common investments to tackle non-communicable diseases, developing the East Africa's Centres of Excellence for Skills and Tertiary Education project funded by the African Development Bank, an initiative that could be replicated for the care of haematological malignancies in other countries in sub-Saharan Africa. TRANSLATION: For the French translation of the abstract see Supplementary Materials section.

Identifiants

pubmed: 34481552
pii: S2352-3026(21)00198-8
doi: 10.1016/S2352-3026(21)00198-8
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e756-e769

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests TSU reports research support for investigator-initiated studies from Celgene, Roche, and Merck Sharp & Dohme, paid to the Fred Hutchinson Cancer Research Center and the US National Cancer Institute, outside the submitted work; and is named on US patent US-10001483-B2 as a federal employee. JMH reports salary support from Arbele ending April, 2021, outside the submitted work. All other authors declare no competing interests.

Auteurs

Clement D Okello (CD)

Uganda Cancer Institute, Kampala, Uganda.

Nixon Niyonzima (N)

Uganda Cancer Institute, Kampala, Uganda.

Marta Ferraresso (M)

Department of Pathology, University of Cambridge, Cambridge, UK.

Sylivestor Kadhumbula (S)

Uganda Cancer Institute, Kampala, Uganda.

Henry Ddungu (H)

Uganda Cancer Institute, Kampala, Uganda.

Katherine Tarlock (K)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Seattle Children's Hospital, Seattle, WA, USA.

Joyce Balagadde-Kambugu (J)

Uganda Cancer Institute, Kampala, Uganda.

Abrahams Omoding (A)

Uganda Cancer Institute, Kampala, Uganda.

Louis Ngendahayo (L)

Anatomical Pathology Service, University Teaching Hospital of Kamenge, Bujumbura, Burundi.

Alfred Karagu (A)

Kenya National Cancer Institute, Nairobi, Kenya.

Julius Mwaiselage (J)

Ocean Road Cancer Institute, Dar es Salaam, Tanzania.

John M Harlan (JM)

University of Washington, Seattle, WA, USA.

Thomas S Uldrick (TS)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA; University of Washington, Seattle, WA, USA.

Suzanne D Turner (SD)

Department of Pathology, University of Cambridge, Cambridge, UK.

Jackson Orem (J)

Uganda Cancer Institute, Kampala, Uganda. Electronic address: jackson.orem@uci.or.ug.

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