Calcineurin-Inhibitor Induced Pain Syndrome in a Heart Transplant Patient.
Journal
Transplantation proceedings
ISSN: 1873-2623
Titre abrégé: Transplant Proc
Pays: United States
ID NLM: 0243532
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
21
07
2021
accepted:
07
08
2021
pubmed:
6
9
2021
medline:
29
10
2021
entrez:
5
9
2021
Statut:
ppublish
Résumé
Calcineurin-inhibitor induced pain syndrome (CIPS) also called the "symmetrical bone syndrome" is a condition describing reversible lower extremity pain in patients after organ transplantation who are receiving calcineurin inhibitors, especially tacrolimus. We present a case of CIPS after orthotopic heart transplant complicated with concurrent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We emphasize the presentation; diagnostic evaluation, and findings. We then discuss the proposed pathophysiologic mechanisms of CIPS and conclude with discussion of management strategies. Additionally, we present a table to guide clinicians in assessing posttransplant bone pain syndromes. To our knowledge, this is the first article to describe a case of CIPS with concurrent SARS-CoV-2 infection.
Identifiants
pubmed: 34481645
pii: S0041-1345(21)00545-5
doi: 10.1016/j.transproceed.2021.08.014
pmc: PMC8410218
pii:
doi:
Substances chimiques
Calcineurin Inhibitors
0
Calcineurin
EC 3.1.3.16
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2630-2635Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
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