Polarized Secretion of APRIL by the Tonsil Epithelium Upon Toll-Like Receptor Stimulation.
Biomarkers
Cell Line
Cell Polarity
Epithelium
/ metabolism
Heparan Sulfate Proteoglycans
/ metabolism
Humans
Immunohistochemistry
Lysosomal-Associated Membrane Protein 1
/ metabolism
Mucous Membrane
/ immunology
Palatine Tonsil
/ immunology
Toll-Like Receptors
/ agonists
Tumor Necrosis Factor Ligand Superfamily Member 13
/ biosynthesis
APRIL
epithelium
mucosa
plasmocytes
survival
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2021
2021
Historique:
received:
27
05
2021
accepted:
23
07
2021
entrez:
6
9
2021
pubmed:
7
9
2021
medline:
21
12
2021
Statut:
epublish
Résumé
In mucosa such as tonsil, antibody-producing plasmocytes (PCs) lie in sub-epithelium space, which is thought to provide a suitable environment for their survival. A proliferation inducing ligand (APRIL) is one key survival factor for PCs present in this area. According to
Identifiants
pubmed: 34484218
doi: 10.3389/fimmu.2021.715724
pmc: PMC8416415
doi:
Substances chimiques
Biomarkers
0
Heparan Sulfate Proteoglycans
0
Lysosomal-Associated Membrane Protein 1
0
Toll-Like Receptors
0
Tumor Necrosis Factor Ligand Superfamily Member 13
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
715724Informations de copyright
Copyright © 2021 Sturm, Quinterot, Guyot, Righini, Daamen, van Kuppevelt and Huard.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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