Case Report: SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism.
COVID-19
SARS-CoV-2
fetal death
mother-to-child transmission
placental thromboembolism
pregnancy
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2021
2021
Historique:
received:
07
03
2021
accepted:
19
07
2021
entrez:
6
9
2021
pubmed:
7
9
2021
medline:
7
9
2021
Statut:
epublish
Résumé
SARS-CoV-2 infection during pregnancy is not usually associated with significant adverse effects. However, in this study, we report a fetal death associated with mild COVID-19 in a 34-week-pregnant woman. The virus was detected in the placenta and in an unprecedented way in several fetal tissues. Placental abnormalities (MRI and anatomopathological study) were consistent with intense vascular malperfusion, probably the cause of fetal death. Lung histopathology also showed signs of inflammation, which could have been a contributory factor. Monitoring inflammatory response and coagulation in high-risk pregnant women with COVID-19 may prevent unfavorable outcomes, as shown in this case.
Identifiants
pubmed: 34485327
doi: 10.3389/fmed.2021.677001
pmc: PMC8415358
doi:
Types de publication
Case Reports
Langues
eng
Pagination
677001Informations de copyright
Copyright © 2021 Marinho, da Cunha, Chimelli, Avvad-Portari, Andreiuolo, de Oliveira-Szejnfeld, Mendes, Gomes, Souza, Guimarães, Goldman, de Oliveira, Rehen, Amim, Tovar-Moll and Prata-Barbosa.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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