Strong correlation between urine and vaginal swab samples for bacterial vaginosis.
BV
G. vaginalis
South Africa
bacterial vaginosis
ddPCR
pregnant women
swab
urine
Journal
Southern African journal of infectious diseases
ISSN: 2313-1810
Titre abrégé: S Afr J Infect Dis
Pays: South Africa
ID NLM: 101646666
Informations de publication
Date de publication:
2021
2021
Historique:
received:
24
03
2020
accepted:
15
03
2021
entrez:
6
9
2021
pubmed:
7
9
2021
medline:
7
9
2021
Statut:
epublish
Résumé
Vaginal swabs have been traditionally used for the diagnosis of bacterial vaginosis (BV). Currently, there are limited studies that have investigated the use of other sample types other than vaginal swabs for the detection of BV from South African populations. This study investigated whether urine can be used for the detection of BV-associated microorganisms in South African pregnant women. One-hundred self-collected vaginal swabs and urine samples were obtained from women presenting for antenatal care at King Edward VIII Hospital in Durban. The BD MAX™ vaginal panel assay was used for diagnosing BV and droplet digital polymerase chain reaction was used to quantify Median copy numbers obtained for This study highlights the appropriateness of urine for the detection of microorganisms associated with BV.
Sections du résumé
BACKGROUND
BACKGROUND
Vaginal swabs have been traditionally used for the diagnosis of bacterial vaginosis (BV). Currently, there are limited studies that have investigated the use of other sample types other than vaginal swabs for the detection of BV from South African populations. This study investigated whether urine can be used for the detection of BV-associated microorganisms in South African pregnant women.
METHODS
METHODS
One-hundred self-collected vaginal swabs and urine samples were obtained from women presenting for antenatal care at King Edward VIII Hospital in Durban. The BD MAX™ vaginal panel assay was used for diagnosing BV and droplet digital polymerase chain reaction was used to quantify
RESULTS
RESULTS
Median copy numbers obtained for
CONCLUSION
CONCLUSIONS
This study highlights the appropriateness of urine for the detection of microorganisms associated with BV.
Identifiants
pubmed: 34485489
doi: 10.4102/sajid.v36i1.199
pii: SAJID-36-199
pmc: PMC8377811
doi:
Types de publication
Journal Article
Langues
eng
Pagination
199Informations de copyright
© 2021. The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article.
Références
BJOG. 2017 Jan;124(1):61-69
pubmed: 27396541
PLoS One. 2013 Oct 04;8(10):e76589
pubmed: 24124575
Trends Microbiol. 2017 Mar;25(3):182-191
pubmed: 27914761
J Clin Microbiol. 1991 Feb;29(2):297-301
pubmed: 1706728
Am J Obstet Gynecol. 2007 Nov;197(5):477.e1-8
pubmed: 17980180
Indian J Med Res. 2015 Jun;141(6):799-806
pubmed: 26205023
J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Jan 1;20(1):52-9
pubmed: 9928730
FEMS Immunol Med Microbiol. 2002 Dec 13;34(4):277-81
pubmed: 12443827
J Infect Dis. 1999 Dec;180(6):1863-8
pubmed: 10558942
J Clin Microbiol. 2014 Jan;52(1):218-25
pubmed: 24197876
PLoS One. 2013;8(1):e53997
pubmed: 23320114
J Infect Dis. 2005 Oct 15;192(8):1372-80
pubmed: 16170754
PeerJ. 2015 Feb 17;3:e780
pubmed: 25737820
BMC Infect Dis. 2017 Jun 5;17(1):394
pubmed: 28583109
PLoS One. 2017 Feb 27;12(2):e0172522
pubmed: 28241058
J Infect Dis. 2006 Sep 15;194(6):828-36
pubmed: 16941351
Am J Obstet Gynecol. 2013 Dec;209(6):505-23
pubmed: 23659989
Clin Infect Dis. 2003 Aug 1;37(3):319-25
pubmed: 12884154
Clin Microbiol Rev. 2016 Apr;29(2):223-38
pubmed: 26864580
Iran J Microbiol. 2014 Dec;6(6):409-14
pubmed: 25926959
PLoS One. 2013 Apr 09;8(4):e60670
pubmed: 23585843
Biomed Res Int. 2015;2015:645853
pubmed: 26078959
Microbiology (Reading). 2016 Mar;162(3):466-475
pubmed: 26747455
Sex Transm Infect. 2016 Nov;92(7):487-491
pubmed: 26965870
Int J Microbiol. 2017;2017:4919404
pubmed: 28831285
Int J STD AIDS. 2020 Mar;31(4):303-311
pubmed: 32050856
AIDS. 1995 Sep;9(9):1093-7
pubmed: 8527084