Game-changing alternatives to conventional fungicides: small RNAs and short peptides.

bio-based fungicides dsRNA fungi oomycetes peptides plant pathogens sustainable agriculture

Journal

Trends in biotechnology
ISSN: 1879-3096
Titre abrégé: Trends Biotechnol
Pays: England
ID NLM: 8310903

Informations de publication

Date de publication:
03 2022
Historique:
received: 06 05 2021
revised: 29 07 2021
accepted: 30 07 2021
pubmed: 8 9 2021
medline: 24 3 2022
entrez: 7 9 2021
Statut: ppublish

Résumé

Fungicide use is one of the core elements of intensive agriculture because it is necessary to fight pathogens that would otherwise cause large production losses. Oomycete and fungal pathogens are kept under control using several active compounds, some of which are predicted to be banned in the near future owing to serious concerns about their impact on the environment, non-targeted organisms, and human health. To avoid detrimental repercussions for food security, it is essential to develop new biomolecules that control existing and emerging pathogens but are innocuous to human health and the environment. This review presents and discusses the use of novel low-risk biological compounds based on small RNAs and short peptides that are attractive alternatives to current contentious fungicides.

Identifiants

pubmed: 34489105
pii: S0167-7799(21)00174-8
doi: 10.1016/j.tibtech.2021.07.003
pii:
doi:

Substances chimiques

Fungicides, Industrial 0
Peptides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

320-337

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests No interests are declared.

Auteurs

Stefano Rosa (S)

Department of Biosciences, University of Milano, I-20133, Milano, Italy.

Paolo Pesaresi (P)

Department of Biosciences, University of Milano, I-20133, Milano, Italy.

Chiara Mizzotti (C)

Department of Biosciences, University of Milano, I-20133, Milano, Italy.

Vincent Bulone (V)

School of Agriculture, Food and Wine, University of Adelaide, Waite Campus, Glen Osmond, South Australia 5064, Australia; Division of Glycoscience, Department of Chemistry, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, AlbaNova University Centre, 10691 Stockholm, Sweden.

Bruno Mezzetti (B)

Department of Agricultural, Food and Environmental Sciences, Marche Polytechnic University, I-60131, Ancona, Italy.

Elena Baraldi (E)

Department of Agricultural and Food Sciences (DISTAL), University of Bologna, I-40126 Bologna, Italy. Electronic address: elena.baraldi@unibo.it.

Simona Masiero (S)

Department of Biosciences, University of Milano, I-20133, Milano, Italy. Electronic address: simona.masiero@unimi.it.

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Classifications MeSH