Protons to Patients: targeting endosomal Na
COVID-19
NHE6
NHE9
endosomal pH
sodium-hydrogen exchanger
viral diseases
Journal
The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
revised:
10
08
2021
received:
14
05
2021
accepted:
23
08
2021
entrez:
7
9
2021
pubmed:
8
9
2021
medline:
22
9
2021
Statut:
ppublish
Résumé
While there is undeniable evidence to link endosomal acid-base homeostasis to viral pathogenesis, the lack of druggable molecular targets has hindered translation from bench to bedside. The recent identification of variants in the interferon-inducible endosomal Na
Identifiants
pubmed: 34490733
doi: 10.1111/febs.16163
pmc: PMC8646450
doi:
Substances chimiques
Protons
0
Sodium-Hydrogen Exchangers
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
5071-5088Subventions
Organisme : DBT-Wellcome Trust India Alliance
ID : IA/E/17/1/503665
Pays : India
Organisme : The Wellcome Trust DBT India Alliance
ID : IA/E/17/1/503665
Informations de copyright
© 2021 Federation of European Biochemical Societies.
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