Pulmonary Benefits of Intervention with Air Cleaner among Schoolchildren in Beijing: A Randomized Double-Blind Crossover Study.

Air Pollutants / analysis Air Pollution Beijing Biomarkers Child Cross-Over Studies Female Humans Interleukin-6 Lung Male Particulate Matter / analysis
PM air filter air pollution inflammation lung function oxidative stress

Journal

Environmental science & technology
ISSN: 1520-5851
Titre abrégé: Environ Sci Technol
Pays: United States
ID NLM: 0213155

Informations de publication

Date de publication:
07 06 2022
Historique:
pubmed: 8 9 2021
medline: 9 6 2022
entrez: 7 9 2021
Statut: ppublish

Résumé

We conducted a crossover study employing air cleaner intervention among 125 schoolchildren aged 9-12 years in a boarding school in Beijing, China. The PM concentrations were monitored, and 27 biomarkers were analyzed. We used the linear mixed-effects model to evaluate the association of intervention/time-weighted PM concentrations with biomarkers. The outcomes showed that air cleaner intervention was associated with FeNO, exhaled breath condensate (EBC) IL-1β, and IL-6, which decreased by 12.57%, 10.83%, and 4.33%, respectively. Similar results were observed in the associations with PMs. Lag 1 day PMs had the strongest relationship with biomarkers, and significant changes were observed in biomarkers such as FEV

Identifiants

DOI: 10.1021/acs.est.1c03146 PMID: 34491046
pubmed: 34491046
doi: 10.1021/acs.est.1c03146
doi:

Substances chimiques

Air Pollutants 0
Biomarkers 0
Interleukin-6 0
Particulate Matter 0

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

7185-7193

Commentaires et corrections

Type : CommentIn

Auteurs

Xiaoyan Yang (X)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Qin Wang (Q)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Air Quality and Health Monitoring, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
ORCID: 0000-0003-0672-9647

Feng Han (F)

National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

Bin Dong (B)

Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China.

Bo Wen (B)

Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China.

Li Li (L)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Hongjie Ruan (H)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Shaoping Zhang (S)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Jian Kong (J)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Hong Zhi (H)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Chong Wang (C)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Jun Wang (J)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Chemistry, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Ming Zhang (M)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Department of Environmental Toxicology, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

Dongqun Xu (D)

Key Laboratory of Environment and Human Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants atmosphériques › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Régions géographiques › Villes › Pékin › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Études croisées › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-6 › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Appareil respiratoire › Poumon › Pulmonary Benefits of Intervention with Air...
questionsmedicales.fr › Mélanges complexes › Matière particulaire › Pulmonary Benefits of Intervention with Air...