Pulse oximetry adoption and oxygen orders at paediatric admission over 7 years in Kenya: a multihospital retrospective cohort study.

audit epidemiology paediatrics protocols & guidelines quality in health care tropical medicine

Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
07 09 2021
Historique:
entrez: 8 9 2021
pubmed: 9 9 2021
medline: 16 9 2021
Statut: epublish

Résumé

To characterise adoption and explore specific clinical and patient factors that might influence pulse oximetry and oxygen use in low-income and middle-income countries (LMICs) over time; to highlight useful considerations for entities working on programmes to improve access to pulse oximetry and oxygen. A multihospital retrospective cohort study. All admissions (n=132 737) to paediatric wards of 18 purposely selected public hospitals in Kenya that joined a Clinical Information Network (CIN) between March 2014 and December 2020. Pulse oximetry use and oxygen prescription on admission; we performed growth-curve modelling to investigate the association of patient factors with study outcomes over time while adjusting for hospital factors. Overall, pulse oximetry was used in 48.8% (64 722/132 737) of all admission cases. Use rose on average with each month of participation in the CIN (OR: 1.11, 95% CI 1.05 to 1.18) but patterns of adoption were highly variable across hospitals suggesting important factors at hospital level influence use of pulse oximetry. Of those with pulse oximetry measurement, 7% (4510/64 722) had hypoxaemia (SpO The adoption of pulse oximetry recommended in international guidelines for assessing children with severe illness has been slow and erratic, reflecting system and organisational weaknesses. Most oxygen orders at admission seem driven by clinical and situational factors other than the presence of hypoxaemia. Programmes aiming to implement pulse oximetry and oxygen systems will likely need a long-term vision to promote adoption, guideline development and adherence and continuously examine impact.

Identifiants

pubmed: 34493522
pii: bmjopen-2021-050995
doi: 10.1136/bmjopen-2021-050995
pmc: PMC8424839
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e050995

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Investigateurs

Lynda Isaaka (L)
George Mbevi (G)
Cynthia Khaenzi (C)
Paul Mwaniki (P)
Mercy Chepkirui (M)
John Wainaina (J)
Livingstone Mumelo (L)
Edith Gicheha (E)
Monica Musa (M)
Naomi Muinga (N)
Muthoni Ogola (M)
Laura Oyiengo (L)
Caroline Mwangi (C)
Fred Were (F)
Juma Vitalis (J)
Nyumbile Bonface (N)
Roselyne Malangachi (R)
Christine Manyasi (C)
Catherine Mutinda (C)
David Kibiwott Kimutai (DK)
Rukia Aden (R)
Caren Emadau (C)
Elizabeth Atieno Jowi (EA)
Cecilia Muithya (C)
Charles Nzioki (C)
Supa Tunje (S)
Penina Musyoka (P)
Wagura Mwangi (W)
Agnes Mithamo (A)
Magdalene Kuria (M)
Esther Njiru (E)
Mwangi Ngina (M)
Penina Mwangi (P)
Rachel Inginia (R)
Melab Musabi (M)
Emma Namulala (E)
Grace Ochieng (G)
Lydia Thuranira (L)
Felicitas Makokha (F)
Josephine Ojigo (J)
Beth Maina (B)
Catherine Mutinda (C)
Mary Waiyego (M)
Bernadette Lusweti (B)
Angeline Ithondeka (A)
Julie Barasa (J)
Meshack Liru (M)
Elizabeth Kibaru (E)
Alice Nkirote Nyaribari (AN)
Joyce Akuka (J)
Joyce Wangari (J)
Amilia Ngoda (A)
Aggrey Nzavaye Emenwa (AN)
Dolphine Mochache (D)
Patricia Nafula Wesakania (PN)
George Lipesa (G)
Jane Mbungu (J)
Marystella Mutenyo (M)
Joyce Mbogho (J)
Joan Baswetty (J)
Ann Jambi (A)
Josephine Aritho (J)
Beatrice Njambi (B)
Felisters Mucheke (F)
Zainab Kioni (Z)
Lucy Kinyua Jeniffer (LK)
Margaret Kethi (M)
Alice Oguda (A)
Salome Nashimiyu Situma (SN)
Nancy Gachaja (N)
Loise N Mwangi (LN)
Ruth Mwai (R)
Irginia Wangari Muruga (IW)
Nancy Mburu (N)
Celestine Muteshi (C)
Abigael Bwire (A)
Salome Okisa Muyale (SO)
Naomi Situma (N)
Faith Mueni (F)
Hellen Mwaura (H)
Rosemary Mututa (R)
Caroline Lavu (C)
Joyce Oketch (J)
Jane Hore Olum (JH)
Orina Nyakina (O)
Faith Njeru (F)
Rebecca Chelimo (R)
Margaret Wanjiku Mwaura (MW)
Ann Wambugu (A)
Epharus Njeri Mburu (EN)
Linda Awino Tindi (LA)
Jane Akumu (J)
Ruth Otieno (R)
Slessor Osok (S)
Seline Kulubi (S)
Susan Wanjala (S)
Pauline Njeru (P)
Rebbecca Mukami Mbogo (RM)
John Ollongo (J)
Samuel Soita (S)
Judith Mirenja (J)
Mary Nguri (M)
Margaret Waweru (M)
Mary Akoth Oruko (MA)
Jeska Kuya (J)
Caroline Muthuri (C)
Esther Muthiani (E)
Esther Mwangi (E)
Joseph Nganga (J)
Benjamin Tanui (B)
Alfred Wanjau (A)
Judith Onsongo (J)
Peter Muigai (P)
Arnest Namayi (A)
Elizabeth Kosiom (E)
Dorcas Cherop (D)
Faith Marete (F)
Johanness Simiyu (J)
Collince Danga (C)
Arthur Otieno Oyugi (AO)
Fredrick Keya Okoth (FK)

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Arch Dis Child. 2011 Mar;96(3):285-90
pubmed: 21220265
BMJ Glob Health. 2018 Jun 26;3(3):e000812
pubmed: 29989086
PLoS One. 2019 Sep 4;14(9):e0221145
pubmed: 31483793
BMC Pediatr. 2017 Apr 5;17(1):99
pubmed: 28381208
BMJ Glob Health. 2016 May 24;1(1):e000028
pubmed: 27398232
BMJ Qual Saf. 2016 May;25(5):303-10
pubmed: 26442789
Ann Intern Med. 2007 Oct 16;147(8):573-7
pubmed: 17938396
Arch Dis Child. 2016 Aug;101(8):694-700
pubmed: 26699537
Crit Care. 2020 Jun 8;24(1):313
pubmed: 32513249
Lancet Glob Health. 2020 Sep;8(9):e1121-e1122
pubmed: 32628910
Lancet Glob Health. 2018 Jan;6(1):e74-e83
pubmed: 29241618
Health Res Policy Syst. 2017 Jan 21;15(1):2
pubmed: 28109282
J Am Med Inform Assoc. 2016 Jan;23(1):184-92
pubmed: 26063746
BMC Med Res Methodol. 2020 Jul 8;20(1):185
pubmed: 32640992
BMJ Glob Health. 2021 Mar;6(3):
pubmed: 33758014
Am J Trop Med Hyg. 2021 Jan 13;:
pubmed: 33534774
Wellcome Open Res. 2020 Nov 5;5:265
pubmed: 33274301
Wellcome Open Res. 2017 Oct 11;2:100
pubmed: 29383331
BMJ Glob Health. 2018 Nov 28;3(6):e001136
pubmed: 30588346
Arch Dis Child. 2018 Nov;103(11):1013-1019
pubmed: 29514814
J Cogn Dev. 2010;11(2):121-136
pubmed: 21743795
Bull World Health Organ. 2017 Apr 1;95(4):288-302
pubmed: 28479624
Int J Infect Dis. 2020 Oct;99:10-18
pubmed: 32781162
Arch Dis Child. 2016 Mar;101(3):223-9
pubmed: 26662925
BMJ Paediatr Open. 2017 Aug 31;1(1):e000083
pubmed: 29637121
Br J Gen Pract. 2016 Aug;66(649):402-3
pubmed: 27481961
PLoS Med. 2020 Oct 23;17(10):e1003300
pubmed: 33095763
BMJ Glob Health. 2017 Oct 23;2(4):e000468
pubmed: 29104769
Health Policy Plan. 2018 Jul 1;33(suppl_2):ii27-ii34
pubmed: 30053035
Glob Health Action. 2019 Dec 13;12(sup1):1761657
pubmed: 32588784
Lancet. 2017 Dec 17;388(10063):3027-3035
pubmed: 27839855
Afr Health Sci. 2014 Jun;14(2):397-407
pubmed: 25320590
Stat Methods Med Res. 2020 Oct;29(10):3076-3092
pubmed: 32390503
PLoS Med. 2019 Dec 31;16(12):e1002987
pubmed: 31891572
BMC Int Health Hum Rights. 2006 Jul 20;6:9
pubmed: 16857044
PLoS Med. 2016 Apr 12;13(4):e1001991
pubmed: 27070913
BMC Med. 2010 Oct 20;8:63
pubmed: 20961442
Int J Tuberc Lung Dis. 2001 Jun;5(6):496-504
pubmed: 11409574
BMC Health Serv Res. 2016 Mar 12;16:87
pubmed: 26968157
Arch Dis Child. 2020 Jul;105(7):648-654
pubmed: 32169853

Auteurs

Timothy Tuti (T)

Health Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya TTuti@kemri-wellcome.org.

Jalemba Aluvaala (J)

Health Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Department of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.

Samuel Akech (S)

Health Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.

Ambrose Agweyu (A)

Health Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.

Grace Irimu (G)

Health Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Department of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.

Mike English (M)

Health Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Nuffield Department of Medicine and Department of Paediatrics, University of Oxford, Oxford, UK.

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