Thrombophilia testing in the era of direct oral anticoagulants.
APS
DOAC
DOAC-Stop
VTE
antiphospholipid syndrome
direct oral anticoagulants
thrombophilia
thrombophilia testing
venous thromboembolism
Journal
Clinical medicine (London, England)
ISSN: 1473-4893
Titre abrégé: Clin Med (Lond)
Pays: England
ID NLM: 101092853
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
pubmed:
9
9
2021
medline:
24
9
2021
entrez:
8
9
2021
Statut:
ppublish
Résumé
Venous thromboembolism (VTE) is increasingly recognised in primary and secondary care practice. The arrival of direct oral anticoagulants (DOACs) has made the management of VTE easier and more convenient. Some patients established on DOACs may need screening for underlying thrombophilias as certain thrombophilic conditions are known to confer a higher thrombosis risk, although the guidelines for when and how to test for a thrombophilia, especially in a patient taking a DOAC, are unclear. This literature review aims to examine when thrombophilia screening should take place in a patient already taking a DOAC, the effect of DOACs on thrombophilia tests, and analyse whether DOACs are safe and effective in both inherited and acquired thrombophilias.
Identifiants
pubmed: 34493545
pii: clinmed.2020-1008
doi: 10.7861/clinmed.2020-1008
pmc: PMC8439516
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e487-e491Informations de copyright
© Royal College of Physicians 2021. All rights reserved.
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