Crushed Corticosteroid Tablets in Peristomal Pyoderma Gangrenosum: A Case Report.
Journal
Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society
ISSN: 1528-3976
Titre abrégé: J Wound Ostomy Continence Nurs
Pays: United States
ID NLM: 9435679
Informations de publication
Date de publication:
Historique:
entrez:
8
9
2021
pubmed:
9
9
2021
medline:
11
9
2021
Statut:
ppublish
Résumé
Peristomal pyoderma gangrenosum (PPG) is a variant of pyoderma gangrenosum (PG). It results from a pathergy response to trauma from effluent from the ostomy or secondary to trauma caused by removal of the ostomy appliance adhesive in contact with the skin. Currently, no evidence-based guidelines for the management of PPG exist. This case study reports a dramatic response to crushed corticosteroid tablets in a patient who proved refractory to first- and second-line treatments of her PPG and several surgeries. Ms T. was a 39-year-old woman with Crohn's disease who underwent several ileostomies, developed PPG, and failed treatment with adalimumab. Her PPG was successfully treated topically with crushed prednisone tablets. We found that crushed corticosteroid tablets were an effective treatment of PPG, due to the ability to reduce pain and allow adhesion of the ostomy appliance.
Sections du résumé
BACKGROUND
BACKGROUND
Peristomal pyoderma gangrenosum (PPG) is a variant of pyoderma gangrenosum (PG). It results from a pathergy response to trauma from effluent from the ostomy or secondary to trauma caused by removal of the ostomy appliance adhesive in contact with the skin. Currently, no evidence-based guidelines for the management of PPG exist. This case study reports a dramatic response to crushed corticosteroid tablets in a patient who proved refractory to first- and second-line treatments of her PPG and several surgeries.
CASE
METHODS
Ms T. was a 39-year-old woman with Crohn's disease who underwent several ileostomies, developed PPG, and failed treatment with adalimumab. Her PPG was successfully treated topically with crushed prednisone tablets.
CONCLUSION
CONCLUSIONS
We found that crushed corticosteroid tablets were an effective treatment of PPG, due to the ability to reduce pain and allow adhesion of the ostomy appliance.
Identifiants
pubmed: 34495940
doi: 10.1097/WON.0000000000000798
pii: 00152192-202109000-00015
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Tablets
0
Types de publication
Case Reports
Journal Article
Langues
eng
Pagination
460-462Informations de copyright
Copyright © 2021 by the Wound, Ostomy and Continence Nurses Society.
Déclaration de conflit d'intérêts
Conflict of Interest: Nothing to declare.
Références
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