Phytochemical Study and Antioxidant Activities of the Water-Soluble Aerial Parts and Isolated Compounds of

Thymus munbyanus subsp. ciliatus antioxidant activity isolated compounds phenolics

Journal

Turkish journal of pharmaceutical sciences
ISSN: 2148-6247
Titre abrégé: Turk J Pharm Sci
Pays: Turkey
ID NLM: 101717890

Informations de publication

Date de publication:
01 09 2021
Historique:
entrez: 9 9 2021
pubmed: 10 9 2021
medline: 10 9 2021
Statut: ppublish

Résumé

The present study aimed to determine the phenolic compounds present in the water-soluble extracts of The aerial parts of Two previously undescribed compounds, namely methyl 2,3,5,6-tetrahydroxybenzoate and 4-hydroxy-5-methoxy-2-oxo-2H-pyran-3-carboxylic acid, and 14 known compounds, including 3 flavonoids; namely 3',5,5',7-tetrahydroxyflavanone, luteolin, and isorhamnetin-3-O-β-glucoside; a sterol glucoside named daucosterol; and 10 phenolic compounds, namely salicylic acid, ferulic acid, pluchoic acid, ethyl caffeate, methyl caffeate, protocatechuic acid, rosmarinic acid, p-coumaric acid, tyrosol, and protocatechuic aldehyde, were isolated from ethyl acetate and The compounds isolated from ethyl acetate and n-butanol extracts exhibited excellent antioxidant and 2,2-diphenyl-1-picrylhydrazyl scavenging activities. All these results highlighted the antioxidant potential of the isolated phenolic compounds and extracts, which could be further utilized for different pharmacological applications.

Identifiants

pubmed: 34496483
doi: 10.4274/tjps.galenos.2020.44538
pmc: PMC8430409
doi:

Types de publication

Journal Article

Langues

eng

Pagination

430-437

Références

J Food Sci Technol. 2015 Oct;52(10):6777-83
pubmed: 26396429
Nat Prod Commun. 2009 Sep;4(9):1251-2
pubmed: 19831038
Methods Enzymol. 1990;186:343-55
pubmed: 2172711
Food Chem. 2013 Jan 1;136(1):34-40
pubmed: 23017389
Toxicol Ind Health. 1993 Jan-Apr;9(1-2):1-21
pubmed: 8380303
Comb Chem High Throughput Screen. 2015;18(5):453-63
pubmed: 25742280
Chem Biodivers. 2012 Jun;9(6):1188-97
pubmed: 22700236
J Agric Food Chem. 2014 May 14;62(19):4251-60
pubmed: 24738928
Biochem Pharmacol. 1991 Oct 9;42(9):1673-81
pubmed: 1656994
Anal Biochem. 1999 May 1;269(2):337-41
pubmed: 10222007

Auteurs

Massika Chaouche (M)

Mentouri Constantine Valorization of Natural Resources University, Department of Chemistry, Bioactive Molecules and Biological Analysis Unit, Constantine, Algeria

İbrahim Demirtaş (İ)

Iğdır University Faculty of Arts and Sciences, Department of Biochemistry, Iğdır, Turkey

Serkan Koldaş (S)

Çankırı Karatekin University Faculty of Science, Department of Chemistry, Çankırı, Turkey

Ali Rıza Tüfekçi (AR)

Çankırı Karatekin University Faculty of Science, Department of Chemistry, Çankırı, Turkey

Fatih Gül (F)

Iğdır University Faculty of Arts and Sciences, Department of Biochemistry, Iğdır, Turkey

Tevfik Özen (T)

Ondokuz Mayıs University Faculty of Arts and Sciences, Department of Chemistry, Samsun, Turkey

Nouioua Wafa (N)

Ferhat Abbas Setif University Faculty of Natural Life and Sciences, Laboratory of Phytotherapy Applied to Chronic Diseases, El Bez, Algeria

Ahcène Boureghda (A)

Mentouri Constantine Valorization of Natural Resources University, Department of Chemistry, Bioactive Molecules and Biological Analysis Unit, Constantine, Algeria

Neslihan Bora (N)

Ondokuz Mayıs University Faculty of Arts and Sciences, Department of Chemistry, Samsun, Turkey

Classifications MeSH