Positive allosteric mechanisms of adenosine A

Adenosine / chemistry Allosteric Regulation / drug effects Analgesia / methods Animals Binding Sites Disease Models, Animal Female GTP-Binding Protein alpha Subunit, Gi2 / chemistry Hyperalgesia / drug therapy Lipids Male Neuralgia / drug therapy Protein Stability / drug effects Rats Rats, Sprague-Dawley Receptor, Adenosine A1 / chemistry Signal Transduction / drug effects

Journal

Nature

ISSN: 1476-4687

Titre abrégé: Nature

Pays: England

ID NLM: 0410462

Informations de publication

Date de publication:
09 2021

Historique:

received: 06 11 2020

accepted: 11 08 2021

pubmed: 10 9 2021

medline: 5 2 2022

entrez: 9 9 2021

Statut: ppublish

Résumé

The adenosine A

Identifiants

DOI: 10.1038/s41586-021-03897-2 PMID: 34497422 PMC: PMC8711093

pubmed: 34497422

doi: 10.1038/s41586-021-03897-2

pii: 10.1038/s41586-021-03897-2

pmc: PMC8711093

mid: NIHMS1760031

doi:

Substances chimiques

Lipids 0

Receptor, Adenosine A1 0

GTP-Binding Protein alpha Subunit, Gi2 EC 3.6.5.1

Adenosine K72T3FS567

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

571-576

Subventions

Organisme : American Heart Association-American Stroke Association

ID : 17SDG33370094

Pays : United States

Organisme : NIGMS NIH HHS

ID : R01 GM132572

Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Références

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