Role of exercise in preventing and restoring gut dysbiosis in patients with inflammatory bowel diseases: A review.

Crohn’s disease Exercise Inflammatory bowel disease Microbiome Pouchitis Ulcerative colitis

Journal

World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448

Informations de publication

Date de publication:
14 Aug 2021
Historique:
received: 26 02 2021
revised: 19 04 2021
accepted: 12 07 2021
entrez: 9 9 2021
pubmed: 10 9 2021
medline: 11 9 2021
Statut: ppublish

Résumé

Inflammatory bowel diseases (IBD) include a spectrum of chronic inflammatory disorders of the gastrointestinal tract whose pathogenesis is yet to be elucidated. The intestinal microbiome has been studied as a causal component, with certain microbiotic alterations having been observed in subtypes of IBD. Physical exercise is a modulator of the intestinal microbiome, causing shifts in its composition that are partially corrective of those observed in IBD; furthermore, physical exercise may be beneficial in patients with certain IBD subtypes. This review studies the effects of physical exercise on the human gut microbiome while investigating pathophysiologic mechanisms that could explain physical activity's clinical effects on patients with IBD.

Identifiants

pubmed: 34497433
doi: 10.3748/wjg.v27.i30.5037
pmc: PMC8384738
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5037-5046

Informations de copyright

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: Authors have nothing to disclose.

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Auteurs

Tilemachos Koutouratsas (T)

Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.

Anastassios Philippou (A)

Department of Basic Medical Sciences, Laboratory of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens 11527, Greece.

George Kolios (G)

Department of Medicine, Laboratory of Pharmacology, Democritus University of Thrace, Alexandroupolis 68100, Greece.

Michael Koutsilieris (M)

Department of Basic Medical Sciences, Laboratory of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens 11527, Greece.

Maria Gazouli (M)

Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece. mgazouli@med.uoa.gr.

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Classifications MeSH