Thyroid Autoimmunity in Adverse Fertility and Pregnancy Outcomes: Timing of Assisted Reproductive Technology in AITD Women.
AITD
ART
Assisted reproductive technology
Infertility
autoimmune thyroid diseases
Journal
Journal of translational internal medicine
ISSN: 2450-131X
Titre abrégé: J Transl Int Med
Pays: Poland
ID NLM: 101673826
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
entrez:
9
9
2021
pubmed:
10
9
2021
medline:
10
9
2021
Statut:
epublish
Résumé
Thyroid autoimmunity (TAI) is prevalent in women of live-birthing age and has independently been associated with complications of fertility and pregnancy, in the case of spontaneous conception or after assisted reproductive technology (ART) treatment. However, it remains challenging to identify causation between infertility and TAI, even interventional trials looking at the impact of levothyroxine (LT4) treatment on fertility and pregnancy outcomes due to differences among study results which related to small scales, impropriate study designs, enrollment criteria of infertility cause and titer/hormone concentration measurements. Furthermore, many questions remain unsettled in ART management in AITD infertile women attempt pregnancy. Therefore, further observational and interventional trials are needed more comprehensive multiple-center, double blinded, and randomized.
Identifiants
pubmed: 34497747
doi: 10.2478/jtim-2021-0001
pii: jtim-2021-0001
pmc: PMC8386333
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
76-83Informations de copyright
© 2021 Jia-Wei Wang et al., published by Sciendo.
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